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This project aims to idetify the proteins that interact with lncRNA IGF1R-AS1 in a prostate cancer cell line, VCaP cells, through LC-MS.
ORGANISM(S): Homo sapiens (Human) 
2026-02-10 | PXD074272 | Pride
Bianconi2012 - EGFR and IGF1R pathway in lung cancer EGFR and IGF1R pathways play a key role in various human cancers and are crucial for tumour transformation and survival of malignant cells. High EGFR and IGF1R expression and activity has been associated with multiple aspects of...
2024-09-02 | BIOMD0000000427 | BioModels
IGF1 and IGF1 receptors (IGF1R) are present in the adult heart and have been shown to be essential for myocardial performance. Insulin-like growth factor 1 (IGF1) is produced in numerous tissues particularly by the liver in response to growth hormone stimulation and is an important factor in the reg...
ORGANISM(S): Mus musculus 
This is a mass spectrometry (MS)-based proteomics dataset, generated to study insulin signaling in a hepatocellular cell model (HepG2 insulin-like growth factor knock-down), at the IR interactome, phos-phoproteome, and proteome level. To induce insulin sensitivity and resistance in HepG2 IGF1R KO ce...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD047011 | Pride
Long-term hematopoietic stem cells (HSCs), short-term HSCs and multipotent progenitor cells (MPPs) were isolated from bone marrow of four mouse strains (WT, H19-deletion, Igf1r-deletion, and double-deletion) and expression profiled with RNAseq. The behavior of the transcriptomes, and in particular...
ORGANISM(S): Mus musculus 
IGF1R controls mechanosignaling in myofibroblasts required for pulmonary alveologenesis.
Detect IGF1R function in postnatal bone marrow mesenchymal stem cell
Transcriptional analysis of tendons from mice with a tenocyte-specific deletion of IGF1R
Whole-genome shRNA to identify sensitizers to MEK and IGF1R inhibitors
Decreased IGF1R Attenuates Senescence and Improves Function in Pancreatic beta-Cells
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