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TranscriptomicsRim15 and Igo1/Igo2 are required for proper transcriptional reprogramming during entry into G0 phase in budding yeast
Transcriptional profiling of yeast strains (WT, rim15Δ, and igo1Δigo2Δ) treated with 100nM rapamycin at 20, 60, 120, 180min post treatment with respect to immediately before treatment as reference. Goal of the experiment was to test whether Rim15 and Igo1/2 are implicated in proper regulating of gen...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-14 | GSE20539 | GEO
UnknownInitiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathway.
Not available
S-EPMC2919320 | biostudies-literature
GenomicsSaccharomyces cerevisiae
Rim15 and Igo1/Igo2 are required for proper transcriptional reprogramming during entry into G0 phase in budding yeast
PRJNA125291 | ENA
UnknownThe Rim15-endosulfine-PP2ACdc55 signalling module regulates entry into gametogenesis and quiescence via distinct mechanisms in budding yeast.
Not available
S-EPMC4072559 | biostudies-literature
ProteomicsEndosulfines Igo1 and Igo2 promote hyperosmotic stress signaling via inhibition of protein phosphatase 2A
The hyperosmotic stress response in budding yeast is a paradigm for cellular responses to physicochemical stimuli that is often used for modeling signal transduction pathways. Here, we describe the phosphatase PP2A-Cdc55 as a novel master regulator of hyperosmotic stress signaling. We show that its ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-11-02 | PXD019646 | Pride
Stress response Phosphorylation Igo2 Gis1 Igo1 Phosphatase Pp2a Saccharomyces cerevisiae Quantitative proteomics Rph1 Hyperosmotic stress Stress signaling Cdc55 Endosulfines 
GenomicsThe Greatwall-Endosulfine switch accelerates autophagic flux during the cell divisions leading to G1 arrest and quiescence in fission yeast
The Greatwall-Endosulfine switch accelerates autophagic flux during the cell divisions leading to G1 arrest and quiescence in fission yeast
PRJNA898803 | ENA
UnknownThe phosphatase inhibitor Sds23 regulates cell division symmetry in fission yeast.
Not available
S-EPMC6822584 | biostudies-literature
Proteomics0518_4 Fission yeast Paa1 interactome
We performed mass-spectrometry analysis of proteins co-purifying with the Paa1, the structural subunit of the PP2A protein phosphatase complex. Paa1 was tagged with YFP at the C-terminus and expressed from its endogenous promoter at its chromosomal locus. After one hour of nitrogen starvation, Paa1-...
ORGANISM(S): Schizosaccharomyces pombe Schizosaccharomyces pombe 
2024-12-02 | PXD047703 | Pride
Fission yeast Paa1-yfp interactome Pp2a 
GenomicsThe Greatwall-Endosulfine-PP2A/B55 pathway controls entry into quiescence by promoting translation of Elongator-tuneable transcripts
The Greatwall-Endosulfine-PP2A/B55 pathway controls entry into quiescence by promoting translation of Elongator-tuneable transcripts
PRJNA1124017 | ENA
ProteomicsIdentification of Endos interacting proteins in Drosophila embryos by immunoprecipitation and LC-MS-MS/MS analysis
The transition from oocyte to embryo requires translation of maternally provided transcripts that in Drosophila is activated by Pan Gu kinase to release a rapid succession of 13 mitotic cycles. Mitotic entry is promoted by several protein kinases that include Greatwall/Mastl, whose endosulfine subst...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-08-09 | PXD036613 | Pride
Endos Syncytial embryo Lc-ms-ms/ms Immunoprecipitation Drosophila 
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