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GenomicsIGSF8 is an Innate Immune Checkpoint and Cancer Immunotherapy Target
IGSF8 is an Innate Immune Checkpoint and Cancer Immunotherapy Target
PRJEB75001 | ENA
UnknownSynapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer.
Not available
S-EPMC7560607 | biostudies-literature
UnknownIgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.
Not available
S-EPMC3418437 | biostudies-literature
UnknownFunctional characterization and clinical significance of IGSF8 in pan-cancer: an integrated bioinformatic and experimental study.
Not available
S-EPMC12420624 | biostudies-literature
UnknownR3HDM4 influences kidney renal clear cell carcinoma progression, immune modulation, and potential links to the IGSF8 immune checkpoint.
Not available
S-EPMC12672864 | biostudies-literature
TranscriptomicsEWI-2 regulates melanoma growth and lung metastasis in a TGF-M-NM-21-dependent manner
EWI-2 (IgSF8) plays a novel, bifunctional role in melanoma cells. EWI-2 inhibits migration, metastasis, EMT-like changes, and CD271-dependent invasion in multiple melanoma cell lines. On the other hand, EWI-2 supports melanoma cell proliferation, survival, and xenograft growth. Consistent with these...
ORGANISM(S): Homo sapiens 
2013-06-15 | E-GEOD-47978 | biostudies-arrayexpress
ProteomicsProteomic analysis of extracellular vesicle released by MCF7 cells in the absence of the tetraspanins CD9, CD81 or CD63
The tetraspanins CD9, CD81, and CD63 are among the most widely used markers of Extracellular Vesicles (EVs) and are also used to isolate the vesicles they decorate. If their function in EVs is largely unknown, they have been suggested to play a role in the sorting of protein cargos into EVs or to re...
ORGANISM(S): Homo sapiens (Human) 
2023-08-03 | PXD042940 | Pride
Tetraspanins Exosomes Mcf7 Ptgfrn Mass spectrometry Cd9 Extracellular vesicles Cd81 Igsf8 Cd63 Proteome Timstof pro 
GenomicsMus musculus
Immunoglobulin superfamily member 8 maintains myeloid leukemia stem cells through inhibition of b-catenin degradation
PRJDB13329 | ENA
UnknownIdentification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.
Not available
S-EPMC4537001 | biostudies-literature
UnknownLineage specific extracellular vesicle-associated protein biomarkers for the early detection of high grade serous ovarian cancer.
Not available
S-EPMC10187430 | biostudies-literature
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