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ProteomicsA proteomic and functional view of intrabacterial lipid inclusion biogenesis in mycobacteria
During infection and granuloma formation, pathogenic mycobacteria accumulate triacylglycerol in the form of Intrabacterial Lipid Inclusions (ILI). These organelles facilitate bacterial evasion from the immune system and serve as a carbon source to sustain bacterial persistence within the infected ho...
ORGANISM(S): Mycobacterium tuberculosis Mycobacterium abscessus 
2025-02-27 | PXD052310 | Pride
Lc-msms Intracellular lipid inclusion Lipid metabolism Apex2 Persistence Ili-associated proteins Proteomic Mycobacterium abscessus Proximity labelling 
ProteomicsProteome analysis in M. abscessus to study intrabacterial lipid inclusion
During infection and granuloma formation, pathogenic mycobacteria accumulate triacylglycerol in the form of Intrabacterial Lipid Inclusions (ILI). These organelles facilitate bacterial evasion from the immune system and serve as a carbon source to sustain bacterial persistence within the infected ho...
ORGANISM(S): Mycobacterium tuberculosis Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) 
2025-05-07 | PXD052312 | Pride
Mycobacterial abscessus proteome 
ProteomicsMapping of mycobacterial lipolytic enzymes involved in triacylglycerol accumulation as intrabacterial lipid inclusions using multi-target inhibitor-like affinity-based probes
Mycobacteria are known for their unique and complex cell wall architecture, characterized by distinct lipid-rich outer layers, making lipid metabolism a central point of their physiological processes. One crucial aspect of all mycobacteria is their ability to metabolize host lipids and to accumulate...
ORGANISM(S): Mycobacterium abscessus 
2025-05-12 | PXD048770 | Pride
Mycobacterium Lc_msms Activity-based protein profiling  multitarget inhibitor-like affinity-based probes  lipid metabolism  cyclipostins & cyclophostin  oxadiazolone 
UnknownIntrabacterial lipid inclusion-associated proteins: a core machinery conserved from saprophyte Actinobacteria to the human pathogen Mycobacterium tuberculosis.
Not available
S-EPMC10699116 | biostudies-literature
UnknownA proteomic and functional view of intrabacterial lipid inclusion biogenesis in mycobacteria.
Not available
S-EPMC11980559 | biostudies-literature
UnknownMolecular characteristics of human adenovirus isolated from the 2024 influenza-like illness outbreaks in Suzhou City, China.
Not available
S-EPMC12265240 | biostudies-literature
TranscriptomicsTNFalpha and IL1beta stimulate differential gene expression in endometrial stromal cells
Cytokines are implicated in the development of inflammatory diseases such as endometriosis. This project was designed to test the hypothesis that specific cytokines that are secreted by macrophages, such as tumor necrosis factor ? (TNF?) and interleukin 1 beta (IL1?), cause gene expression changes i...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-40007 | biostudies-arrayexpress
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