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ProteomicsAlzheimer Disease model detergent insoluble proteomes
Characterizing the detergent insoluble brain proteome of sporadic late-onset Alzheimer’s disease (LOAD) has identified proteins and pathways associated with disease pathogenesis. Similar studies in early onset Alzheimer’s disease cases due to presenilin-1 mutations (PS1-EOAD), along with more detail...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2022-03-01 | PXD005347 | Pride
In-gel digestion Dquan Neurodegeneration In house xic quantitation 
ProteomicsProtein accumulation post-LASIK surgery in granular corneal dystrophy type II patients involves altered proteolytic processing of transforming growth factor beta-induced protein (TGFBIp)
his study present the protein profile of diseased cornea from granular corneal dystrophy patients developing protein accumulation after LASIK surgery. Extracted ion chromatography (XIC) label free quantification was perform using Mascot Distiller software. In addition, 2D-PAGE followed by western bl...
ORGANISM(S): Homo sapiens (Human) 
2016-02-19 | PXD001997 | Pride
Cornea Tripletof 5600+ Xic quantification 2d-page Granular corneal dystrophy 
ProteomicsAlzheimer Disease (AD) and AD model detergent insoluble proteomes
Characterizing the detergent insoluble brain proteome of sporadic late-onset Alzheimer’s disease (LOAD) has identified proteins and pathways associated with disease pathogenesis. Similar studies in early onset Alzheimer’s disease cases due to presenilin-1 mutations (PS1-EOAD), along with more detail...
ORGANISM(S): Homo sapiens (Human) 
2019-06-25 | PXD005321 | Pride
In-gel digestion Dquan Neurodegeneration In house xic quantitation 
ProteomicsEstablishment of dimethyl labeling-based quantitative acetylproteomics in Arabidopsis
Protein acetylation, one of many types of post-translational modifications (PTMs), is involved in a variety of biological and cellular processes. In the present study, we applied both CsCl density gradient (CDG) centrifugation-based protein fractionation and a dimethyl-labelling-based 4C quantitativ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-03-14 | PXD006177 | Pride
Cscl density gradient (cdg) centrifugation Stable isotope dimethyl labelling Arabidopsis Squa-d Acetylproteomics 4c proteomic workflow Quantitative ptm proteomics 
UnknownEstablishment of Dimethyl Labeling-based Quantitative Acetylproteomics in Arabidopsis.
Not available
S-EPMC5930405 | biostudies-literature
ProteomicsProteomics of Fuchs Endothelial Corneal Dystrophy support that the extracellular matrix of Descemet¹s membrane is Disordered
Fuchs’ endothelial corneal dystrophy is major corneal disorder in the western world affecting the innermost part of the cornea, which leads to visual impairment. The morphological changes observed in Fuchs’ endothelial corneal dystrophy is well described, however, much less in known of the pathology...
ORGANISM(S): Homo sapiens (Human) 
2014-05-27 | PXD000746 | Pride
Itraq quantification Fuchs' endothelial corneal dystrophy Xic quantification 
ProteomicsVaginal secretory proteome dynamically changes across the early and mid-trimesters of pregnancy
This study investigates the dynamic alterations in high vaginal fluid (HVF) proteome and its correlation with physiological changes during progression of term pregnancy. The HVF samples were collected at three time points as defined as V1 (6-12 weeks), V2 (18-20 weeks) and V3 (26-28 weeks) and SWAT...
ORGANISM(S): Homo sapiens (Human) 
2021-01-28 | PXD021811 | Pride
Pregnancy Human vaginal fluid Longitudinal study Mrm Swath ms 
ProteomicsSalivary proteome signatures in the early and middle stages of human pregnancy with term birth outcome
This prospective study is to find changes in salivary protein expressions from first to early third trimester of pregnancy in normal term birth using SWATH-MS strategy. Saliva at three periods of gestation, 6-13 (V1), 18-21(V2), and 26-29 (V3) weeks from 20 singleton pregnant women were used in ...
ORGANISM(S): Homo sapiens (Human) 
2020-09-28 | PXD014800 | Pride
Pregnancy Swath Human Saliva 
ProteomicsVaginal secretory proteome dynamically changes across the early and mid-trimesters of pregnancy
This study investigates the dynamic alterations in high vaginal fluid (HVF) proteome and its correlation with physiological changes during progression of term pregnancy. The HVF samples were collected at three time points as defined as V1 (6-12 weeks), V2 (18-20 weeks) and V3 (26-28 weeks) and SWAT...
ORGANISM(S): Homo sapiens (Human) 
2021-01-29 | PXD014846 | Pride
Pregnancy Human vaginal fluid Longitudinal study Swath ms 
ProteomicsAPPLICATION OF A NOVEL PEPTIDE SPECTRAL LIBRARY USING SWATH ANALYSIS FOR THE QUANTITATION OF PROTEINS IN EX-DIAGNOSTIC CLINICAL SERUM SAMPLES FROM SHEEP
This project applies SWATH approach to analyse ex-diagnostic sheep serum samples from actual clinical cases submitted to The University of Queensland's School of Veterinary Science, Veterinary Laboratory Services (VLS) compared with serum of normal sheep.
ORGANISM(S): Ovis aries 
2022-11-15 | PXD005077 | Pride
Nanolc-nanoesi-ms/ms Data independent acquisition Sick sheep Swath Peptide spectral library Proteogenomics Circulating acellular proteome Tripletof 5600+ Sample preparation 
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