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MetabolomicsEcological adaptation and succession of human fecal microbial communities in an automated in vitro fermentation system
Longitudinal studies of gut microbiota following specific interventions are vital for understanding how they influence host health. However, robust longitudinal sampling of gut microbial communities is a major challenge, which can be addressed using in vitro fermenters hosting complex microbial comm...
2021-07-15 | MTBLS2531 | MetaboLights
MetabolomicsIn Vitro and In Vivo Metabolomic Profiling after Infection with Virulent Newcastle Disease Virus
Newcastle disease (ND) is an acute, febrile, and highly contagious disease caused by the virulent Newcastle disease virus (vNDV) worldwide. The disease causes serious economic losses to the poultry industry. However, the metabolic changes caused by vNDV infection remain unclear. The objective of thi...
2019-12-20 | MTBLS1115 | MetaboLights
ProteomicsKinetics of peptides generated during static INFOFEST in vitro digestion of mealworms and crickets compared to chicken breast
Mealworms and crickets are edible protein-dense insects that can be produced more sustainably than animal proteins from livestock, and are therefore promising alternative protein sources for human consumption. The protein amount provided by a food source is, however, dependent on the protein digesti...
ORGANISM(S): Acheta domesticus Gallus gallus (Chicken) Tenebrio molitor 
2023-06-23 | PXD041373 | Pride
Acheta domesticus Insect  peptide pattern  infogest  protein hydrolysis  tenebrio molitor Chicken 
ProteomicsChlorella vulgaris Protein Isolate Effectively Protects Lacticaseibacillus rhamnosus GG Viability During processing, Storage, and In vitro Digestion
This study examined the protective effect of Chlorella vulgaris protein isolate (CPI) on the biological activity of Lacticaseibacillus rhamnosus GG (LGG) during lyophilisation, storage, and in vitro digestion. Prior to lyophilisation, probiotic hydrogels were either fermented to pH 4.5 (CF) or left ...
ORGANISM(S): Chlorella vulgaris (Green alga) Lactobacillus rhamnosus GG 
2026-01-06 | PXD066171 | Pride
Probiotics Encapsulation Microalgae Protein isolate Viability In vitro digestion 
TranscriptomicsDifferential virulence gene expression in the pathogenic dermatophyte Arthroderma benhamiae in vitro versus infection
Although dermatophytes are the most common agents of superficial mycoses in humans and animals, the molecular basis of the pathogenicity of these fungi is largely unknown. In vitro digestion of keratin by dermatophytes is associated with the secretion of multiple proteases, which are assumed to be r...
ORGANISM(S): Arthroderma benhamiae 
2010-03-04 | E-GEOD-15873 | biostudies-arrayexpress
ProteomicsUrinary PRM analysis of early type 1 diabetes
Chronic hyperglycemia is known to disrupt the proteolytic milieu, initiating compensatory and maladaptive pathways in the diabetic kidney. Such changes in intrarenal proteolysis can be captured in the urinary peptidome. We thus examined the urinary peptidomes of otherwise healthy youths with type 1 ...
ORGANISM(S): Homo Sapiens 
2020-01-01 | PXD012389 | panorama
ProteomicsThe fate of bioaccessible coeliac toxic motifs and IgE epitopes during simulated gastro-intestinal digestion of pizza base
Understanding how food processing may modify allergen bioaccessibility and the evolution of immunologically active peptides in the gastrointestinal tract is essential if knowledge-based ap-proaches to reducing the allergenicity of food is to be realised. A soy-enriched wheat-based pizza base was sub...
ORGANISM(S): Glycine max Triticum aestivum (Wheat) 
2022-08-12 | PXD031067 | Pride
Allergen In vitro digestion Ige epitope Allergenicity risk assessment. Coeliac toxic motif Wheat Soy Gluten Mass spectrome-try 
GenomicsEffect of human child or adult digestion reproduced in a dynamic in vitro gastrointestinal model on Cryptosporidium parvum transcriptome
Effect of human child or adult digestion reproduced in a dynamic in vitro gastrointestinal model on Cryptosporidium parvum transcriptome
PRJNA1130464 | ENA
TranscriptomicsDNA microarray comparison of gene expression patterns in Paracoccidioides brasiliensis mycelia and yeasts in vitro.
Paracoccidioides brasiliensis is a thermally dimorphic fungus, which causes the most prevalent systemic mycosis in Latin America. Infection is initiated by inhalation of conidia or mycelial fragments by the host, followed by further differentiation into the yeast form. Information regarding gene e...
ORGANISM(S): Paracoccidioides brasiliensis 
2009-05-07 | E-GEOD-15511 | biostudies-arrayexpress
ProteomicsBile Salts Enhance the Susceptibility of the Allergenic Lipid Transfer Protein from Peach, Pru p 3 to in vitro gastrointestinal digestion
Sensitisation to the lipid transfer protein Pru p 3 is associated with severe allergic reactions to peach, the proteins stability being thought to play a role in its allergenicity. Lipid binding increases susceptibility of Pru p 3 to digestion and so the impact of bile salts on the in vitro gastroin...
ORGANISM(S): Prunus persica 
2023-10-24 | PXD037801 | Pride
Disulphide bonds Immunoactivity Digestibility Bile salts Pru p 3 
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