Interferon-stimulated genes

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Homo sapiens (484)
Mus musculus (291)
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CHEBI ID

CHEBI:134623 (1)
CHEBI:57642 (1)
CHEBI:59776 (1)
CHEBI:47878 (1)
CHEBI:27404 (1)
CHEBI:34018 (1)
CHEBI:30923 (1)
CHEBI:89930 (1)
CHEBI:17050 (1)
CHEBI:73858 (1)
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CHEBI:16002 (1)
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CHEBI:16335 (1)
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CHEBI:18012 (1)
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CHEBI:44897 (1)
CHEBI:30744 (1)
CHEBI:30915 (1)
CHEBI:15354 (1)
CHEBI:30769 (1)

Metabolite Name

Succinic_acid (1)
Oxoglutaric_acid (1)
Oxalacetic_acid (1)
Fumaric_acid (1)
Citric_acid (1)
Pyruvic_acid (1)
Phosphoenolpyruvic_acid (1)
L-Lactic_acid (1)
Hexose-phosphate (1)
Dihydroxyacetone_phosphate (1)
3-Phosphoglyceric_acid (1)
Myristic acid d27 (1)
L-cystine (1)
5,6-dihydroxyindole (1)
L-cysteinylglycine disulfide (1)
4-hydroxy-2-oxoglutarate (1)
(S)-AMPA (1)
Sn-glycero-3-phosphocholine (1)
1-octadecanoyl-sn-glycero-3-phosphocholine (1)
D-Glyceraldehyde 3-phosphate (1)
D-glucarate (1)
Choline (1)
Adenosine (1)

IsPrivate

False (1)

First Public Date

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2018 (38)
2017 (38)
2015 (25)
2016 (17)
2013 (6)

Modelling Approach

Ordinary differential equation model (1)

Study type

Transcription profiling by array (300)
RNA-seq of coding RNA (32)
Unknown experiment type (9)
ChIP-seq (8)
ChIP-chip by tiling array (3)
Other (3)
Transcription profiling by RT-PCR (2)
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Human - High-throughput sequencing (1)
Proteomic profiling by mass spectrometer (1)
Comparative genomic hybridization by array (1)
MicroRNA profiling by array (1)
DNA-seq (1)
Methylation profiling by array (1)
RNA-seq of coding RNA from single cells (1)
RNA-seq of non coding RNA (1)

Release Date

2022 (262)
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2015 (131)
2019 (129)
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2014 (120)
2016 (118)
2013 (106)
2012 (80)
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2011 (54)
2008 (41)
2026 (33)
2009 (33)
2007 (30)
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2006 (12)
2004 (11)
2003 (4)
2002 (3)
1998 (3)
1997 (2)
2000 (1)
1999 (1)

Lab affiliation

Institute of Virology - Viral Immunopathology, Faculty of Medicine, Technical University Munich (4)
Technical University Munich, Faculty of Medicine, Institute of Virology, Viral Immunopathology, Schneckenburger Str. 8, D-81675 Munich, Germany (4)
Technical University of Munich, School of Medicine, Institute of Virology, 81675 Munich, Germany (4)
Cambridge Institute for Medical Research, University of Cambridge (2)
3Division of Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden (1)
Animal Clinical Pathology, College of Animal Science and Veterinary Medicine, Shandong Agricultural University,Shandong Province, China (1)
Biomolecular characterization unit, Center for Sustainable Resource Science, RIKEN (1)
Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK (1)
Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK (1)
Cancer Science Institute of Singapore (CSI), National University of Singapore (NUS) (1)
Cheeloo College of Medicine, Shandong University, Jinan 250002, PR.China. Department of Hepatobiliary Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China. Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, Hefei 230001, China. Anhui Provincial Clinical Research Center for Hepatobiliary Diseases, Hefei 230001, China. (1)
Cheeloo College of Medicine, Shandong University, Jinan 250002, PR.China. Department of Hepatobiliary Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China. Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, Hefei 230001, China. Anhui Provincial Clinical Research Center for Hepatobiliary Diseases, Hefei 230001, China. (1)
Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver BC, Canada (1)
Department of Biochemistry and Molecular Biology; Michael Smith Laboratories; University of British Columbia (1)
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA (1)
Department of Microbiology Icahn School of Medicine at Mount Sinai (1)
Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA (1)
Department of Virology and Viral Animal Diseases, National Veterinary Research Institute - State Research Institute, Pulawy, Poland (1)
Director, Robert H. Lurie Comprehensive Cancer Center Jesse, Sara, Andrew, Abigail, Benjamin and Elizabeth Lurie Professor of Oncology Professor of Medicine (Hematology and Oncology) and Biochemistry and Molecular Genetics (1)
Discipline of Pathology, Charles Perkins Centre, University of Sydney, Australia (1)
Head of Proteomics University of Oslo and Oslo University Hospital (1)
Head of the Crick Mass Spectrometry Proteomics Platform (1)
Human Biology Division, Fred Hutchinson Research Center, Seattle, WA, USA. (1)
MRC University of Glasgow Centre for Virus Research (1)
Max F. Perutz Laboratories (MFPL), University of Vienna, Vienna Biocenter (VBC), Austria (1)
Microbiology department at Icahn School of Medicine at Mount Sinai (1)
PPPSRU USDA ARS (1)
Penengo Lab, Institute of Molecular Cancer Research, University of Zurich, Switzerland (1)
Princeton University (1)
Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain (1)

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Global Interferon-stimulated Genes Interactome Network

Interferon-stimulated genes (ISGs) form the backbone of innate immune system and are pivotal for limiting intra- and intercellular viral replication and spread. We conducted a mass spectrometry–based survey to understand the fundamental organization of the innate immune system and to explore molecul...

ORGANISM(S): Homo sapiens (Human)

2019-03-01 | PXD012274 | Pride

Induction of interferon-stimulated genes on the IL-4 response axis by Epstein-Barr virus infected human B cells; relevance to cellular transformation.

Epstein-Barr virus (EBV) is an oncogenic virus that is associated with the pathogenesis of several human lymphoid malignancies, including Hodgkin's lymphoma. Infection of normal resting B cells with EBV results in activation to lymphoblasts that are phenotypically similar to those generated by physi...

ORGANISM(S): Homo sapiens

2014-02-03 | E-GEOD-45829 | biostudies-arrayexpress

The ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes

The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Ut...

ORGANISM(S): Homo sapiens (Human)

2026-03-11 | PXD045812 | Pride

Viral replication Live-cell imaging Sars-cov-2 Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics

The ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes

ORGANISM(S): Homo sapiens (Human)

2026-03-09 | PXD045783 | Pride

Viral replication Live-cell imaging Sars-cov-2 Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics

The ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes

ORGANISM(S): Homo sapiens (Human)

2026-04-30 | PXD045916 | Pride

Viral replication Live-cell imaging Sars-cov-2 Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics

The ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes