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ProteomicsThe ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes
The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Ut...
ORGANISM(S): Homo sapiens (Human) 
2026-03-11 | PXD045812 | Pride
Viral replication Live-cell imaging Sars-cov-2 Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics 
ProteomicsThe ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes
The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Ut...
ORGANISM(S): Homo sapiens (Human) 
2026-03-09 | PXD045929 | Pride
Viral replication Live-cell imaging Sars-cov-2 Rtcb Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics 
ProteomicsThe ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes
The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Ut...
ORGANISM(S): Homo sapiens (Human) 
2026-03-09 | PXD045783 | Pride
Viral replication Live-cell imaging Sars-cov-2 Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics 
ProteomicsThe ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes
The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Ut...
ORGANISM(S): Homo sapiens (Human) 
2026-04-30 | PXD045916 | Pride
Viral replication Live-cell imaging Sars-cov-2 Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics 
ProteomicsGlobal Interferon-stimulated Genes Interactome Network
Interferon-stimulated genes (ISGs) form the backbone of innate immune system and are pivotal for limiting intra- and intercellular viral replication and spread. We conducted a mass spectrometry–based survey to understand the fundamental organization of the innate immune system and to explore molecul...
ORGANISM(S): Homo sapiens (Human) 
2019-03-01 | PXD012274 | Pride
Isg interactome Ifn Ap-lc-ms/ms 
ProteomicsFluAV vRNP interactome - A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape
Interferon-stimulated genes (ISGs) form the backbone of innate immune system and are pivotal for limiting intra- and intercellular viral replication and spread. We conducted a mass spectrometry–based survey to understand the fundamental organization of the innate immune system and to explore molecul...
ORGANISM(S): Homo sapiens (Human) 
2019-03-01 | PXD012275 | Pride
Influenza Rnps Fluav Ap-lc-ms/ms 
TranscriptomicsChIP-chip from KG-1 cells with HIV Tat
HIV-1 Tat can modulate the expression of both HIV and cellular genes. In antigen-presenting cells Tat induces the expression of a subset of interferon-stimulated genes (ISGs) in the absence of interferons (IFNs). We investigated the genome-wide Tat association with cellular promoters in immature den...
ORGANISM(S): Homo sapiens 
2013-05-31 | E-GEOD-42191 | biostudies-arrayexpress
TranscriptomicsType I and II Interferon-Stimulated Genes in Murine Primary Bone Marrow Macrophages
We used microarrays to compare interferon-alpha (IFNa)- and interferon-gamma (IFNg)-stimulated genes under an equivalent biological input. The goal was to compare IFNa- and IFNg-stimulated genes, as well as to identify common and distinct sets of type I and II ISGs. Bone marrow macrophages derived f...
ORGANISM(S): Mus musculus 
2012-02-15 | E-GEOD-35825 | biostudies-arrayexpress
UnknownEstablishment and Validation of an Interferon-Stimulated Genes (ISGs) Prognostic Signature in Pan-cancer Patients: A Multicenter, Real-world Study.
Not available
S-EPMC9254476 | biostudies-literature
GenomicsInduction of antiviral Interferon-Stimulated Genes (ISGs) by neuronal STING promotes the resolution of pain
Induction of antiviral Interferon-Stimulated Genes (ISGs) by neuronal STING promotes the resolution of pain
PRJNA992544 | ENA
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