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This study assesses the stability of metabolite levels in plasma and liver interstitial fluid (IF) from mice subjected to different handling times prior to extraction. Blood and tissues from female C57BL/6J mice were collected and either processed immediately or held on ice for 5, 10, or 30 minut...

2025-12-30 | MTBLS13164 | MetaboLights
In order to investigate the effect of the NLRP3 inflammasome on the regeneration of enthesis, we established an enthesis injury and repair model in wild-type and NLRP3-/- mice. The interstitial fluid of enthesis was extracted, and untargeted metabolomics was conducted to discover differential metabo...
2025-07-08 | MTBLS12150 | MetaboLights

This study presents quantitative metabolomic measurements of plasma and tissue interstitial fluids (IF) collected from healthy C57BL/6J mice. Using liquid chromatography–mass spectrometry (LC–MS) and external chemical standards, absolute concentrations were determined for over one hundred polar m...

2025-12-30 | MTBLS13165 | MetaboLights
The skeletal muscle interstitial space is the extracellular region around myofibres and mediates crosstalk between resident cell types. We applied a proteomic workflow to characterise the human skeletal muscle interstitial fluid proteome at rest and in response to exercise. Following exhaustive exer...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-01-16 | PXD058818 | Pride
MS-based proteomics study of the interstitial fluid of breast cancer of mice lacking or overexpressing cathepsin B
ORGANISM(S): Mus musculus (Mouse) 
2016-03-31 | PXD002585 | Pride
Cyclic mechanical loads applied to the skeleton increase bone formation. Dynamic fluid flow is a potent anabolic stimulus for cultured osteoblasts. In this study, gene profiles involved in mediating the anabolic response of MC3T3 osteoblasts to dynamic fluid flow are investigated. MC3T3 osteoblast R...
ORGANISM(S): Mus musculus 
Proteomic characterization of human dermal interstitial fluid compared to matching serum and plasma.
ORGANISM(S): Homo sapiens (Human) 
2019-05-21 | PXD012658 | Pride
Proteomics analysis of interstitial fluid from 35 human breast cancers.
ORGANISM(S): Homo sapiens (Human) 
2020-11-11 | PXD001686 | Pride
Dermal interstitial fluid (ISF) shows promise for novel skin diagnostics and as an alternative to invasive blood tests. This dataset includes ISF sampled via a microneedle device from two ex vivo human abdominal skin specimens and the forearms of ten healthy volunteers. Paired blood samples via fing...
ORGANISM(S): Homo sapiens (Human) 
2025-08-23 | PXD064496 | Pride
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