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ProteomicsComprehensive Proteomic Characterization of Human Pancreatic Cyst Fluid from Intraductal Papillary Mucinous Neoplasm by LC-MS/MS
Intraductal papillary mucinous neoplasm (IPMN) is a duct-dilating precancerous lesion that grows in pancreatic ducts and is accompanied by the production of mucinous fluid. In recent years, its cystic fluid has been used molecularly for the differential diagnosis of other cystic tumors and malignanc...
ORGANISM(S): Homo sapiens (Human) 
2017-08-22 | PXD005671 | Pride
Pancreatic cyst Protein mutation Intraductal papillary mucinous neoplasm 
ProteomicsQuantitative Proteomic Profiling for Predicting Grade of Dysplasia in Intraductal Papillary Mucinous Neoplasm using Pancreatic Cyst Fluid
The increased number of pancreatic cyst lesions (PCLs) have been detected through the development of abdominal imaging techniques, such as computed tomography (CT), magnetic resonance imaging (MRI), and endoscopic ultrasound (EUS). However, accurate classification of cystic lesions is difficult beca...
ORGANISM(S): Homo sapiens (Human) 
2020-09-06 | PXD016127 | Pride
Mucinous cystic neoplasm (mcn) Pancreatic cyst fluid Biomarkers Intraductal papillary mucinous neoplasm (ipmn) Serous cystic neoplasm (scn) Lc-ms/ms 
ProteomicsQuantitative Proteomic Analysis of Pancreatic Cyst Fluid Proteins Associated with Malignancy in Intraductal Papillary Mucinous Neoplasms
Intraductal papillary mucinous neoplasm (IPMN) is a benign tumor that grows within the pancreatic ducts characterized by the production of thick mucinous fluid by surrounding tumor cells. IPMN is the most important precursor lesion for pancreatic cancer that is the fourth most common cause of cancer...
ORGANISM(S): Homo sapiens (Human) 
2018-05-01 | PXD008302 | Pride
Ipmn dysplasia Mucinous cystic neoplasm (mcn) Biomarker candidates Pancreatic cyst fluid Intraductal papillary mucinous neoplasm (ipmn) Lc-ms/ms 
TranscriptomicsA GNAS mutation found in pancreatic intraductal papillary mucinous neoplasms induces drastic alterations of gene expression profiles with upregulation of mucin genes.
GNAS, a gene encoding G-protein stimulating alpha subunit, is frequently mutated in intraductal papillary mucinous neoplasms (IPMNs), which is an indolent and slow-growing pancreatic neoplasm that secretes abundant mucin. GNAS mutation is not observed in conventional ductal adenocarcinomas of the pa...
ORGANISM(S): Homo sapiens 
2014-02-04 | E-GEOD-53350 | biostudies-arrayexpress
GenomicsA revised model of clonal evolution of intraductal papillary mucinous neoplasm-related pancreatic carcinogenesis
A revised model of clonal evolution of intraductal papillary mucinous neoplasm-related pancreatic carcinogenesis
PRJNA464916 | ENA
TranscriptomicsExpression data from epithelial cells during the process of multistep pancreatic carcinogenesis
The host antitumor immunity changes drastically during carcinogenesis. Intraductal papillary-mucinous neoplasm (IPMN) of the pancreas is a precursor lesion of pancreatic cancer and progresses according to adenoma-carcinoma sequence. We found that the host antitumor immune reaction changes from an im...
ORGANISM(S): Homo sapiens 
2010-12-23 | E-GEOD-19650 | biostudies-arrayexpress
ProteomicsHuman serum proteomics of pancreatic cancer
We analyzed a total of 60 human serum samples, including healthy controls, patients with intraductal papillary mucinous neoplasms, and patients with pancreatic ductal adenocarcinoma. Parallel reaction monitoring liquid chromatography–tandem mass spectrometry was performed for quantitative analysis.
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD067770 | Pride
Human Pancreas Lc-msms 
ProteomicsHuman serum proteomics of pancreatic cancer
We analyzed a total of 60 human serum samples, including healthy controls, patients with intraductal papillary mucinous neoplasms, and patients with pancreatic ductal adenocarcinoma. Data-dependent acquisition liquid chromatography–tandem mass spectrometry was performed for proteomic profiling.
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD067759 | Pride
Human Lc-msms Serum Pancreas 
Methylation profilingA revised model of clonal evolution of intraductal papillary mucinous neoplasm-related pancreatic carcinogenesis
Similarity of DNA methylation profile observed in the multi-regions from the branch-off subtype intraductal papillary mucinous neoplasm-related pancreatic adenocarcinoma
ORGANISM(S): Homo sapiens 
2019-05-08 | GSE114163 | GEO
UnknownConfocal Endomicroscopy Characteristics of Different Intraductal Papillary Mucinous Neoplasm Subtypes.
Not available
S-EPMC5558896 | biostudies-literature
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