Intraepithelial neoplasia

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Unknown (1699)
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Organisms

Mus musculus (531)
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Organisms

Homo sapiens (82)
Mus musculus (76)
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human vaginal metagenome (3)
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unidentified (1)
human skin metagenome (1)
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mouse gut metagenome (1)
Homo (1)
metagenome (1)

Repository

biostudies-arrayexpress (1017)
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geo (138)
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pride (13)
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EVA (2)
dbGaP (1)
GNPS (1)

Tissue

Blood serum (5)
Blood (1)
Cell culture (1)
Epithelium of pancreatic duct (1)
Malignant cell (1)
PanIN cell (1)
Pancreas (1)
Pancreatic duct (1)
Pancreatic ductal adenocarcinoma cell (1)
Prostate gland (1)
Uterine cervix (1)

Disease

Normal (8)
Neoplasms (3)
Prostate cancer (2)
Breast cancer (2)
Barrett's esophagus (2)
Stomach Neoplasms (2)
Vulvar intraepithelial neoplasia (1)
MPIN (mouse prostatic intraepithelial neoplasia) (1)
Lymphoblastic leukemia (1)
Tumor stage T2+ (1)
T. circumcincta infection (1)
Bladder carcinoma (1)
Asthma (1)
Colorectal cancer recurrence-free (1)
MPIN (murine prostatic intraepithelial neoplasia) (1)
Infected (1)
Mock infected (1)
Porphyria NOS (1)
Infected (1)
Cancer cell line pool (1)
Bladder cancer (1)
IBDV infected (1)
Acute Myeloid Leukemia (1)
Mastitis (1)
Chicken Anaemia Virus infected (1)
Breast carcinoma (1)
Cervical cancer (1)
Barrett esophagus (1)
The most important risk factor for developing esophageal adenocarcinoma (EAC) is the presence of a Barrett esophagus (BE), a condition in which, due to chronic gastro-esophageal reflux, the epithelium of the distal esophagus has been replaced by columnar epithelium containing specialized intestinal metaplasia. Patients with low grade intraepithelial neoplasia (LGIN) are therefore kept under more close observation and/or undergo more frequent endoscopic surveillance (every 6 to 12 months). Endoscopic surveillance for BE is uncomfortable to the patient and cost-effectiveness is not evidence-based (1)
Esophageal cancer, Esophageal intraepithelial neoplasia,gastric cancer, gastric adenoma, colorectal cancer, colorectal adenoma, Barrett’s esophageal cancer (1)

Technology Type

Mass Spectrometry (13)
Shotgun proteomics (6)
Mass spectrometry (3)
Bottom-up proteomics (3)
Data-independent acquisition (3)
NextSeq 500, ILLUMINA (1)
ILLUMINA, NextSeq 500, HiSeq X Ten (1)
Illumina HiSeq 2500, ILLUMINA (1)
NMR spectroscopy (1)
Data-dependent acquisition (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (49)
Illumina HiSeq 2000 (29)
NextSeq 500 (14)
Illumina HiSeq 2500 (11)
Illumina MiSeq (7)
Illumina HiSeq 3000 (6)
ScanArray 4000 [PerkinElmer] (5)
ScanArray 5000 [PerkinElmer] (5)
Generation III Array Scanner [Amersham] (5)
NextSeq 550 (5)
Illumina Genome Analyzer IIx (4)
Flow Cytometer (4)
Illumina HiSeq 4000 (4)
Illumina NovaSeq X (3)
NA (3)
Thermomixer (2)
Illumina HiSeq (2)
418 [Affymetrix] (2)
GenePix 4000B [Axon Instruments] (2)
Illumina Genome Analyzer II (2)
CellRanger v2.1.0 (1)
10X Genomics Chromium Single Cell Kit (1)
Real-time PCR Thermal Cycler (1)
DNBSEQ-G50 (1)
10x Genomics Chromium (1)
Qiagen RNeasy micro Kit (1)
BD FACSAria III (1)
Agfa 1236s (1)
ScanArray Lite [PerkinElmer] (1)
ScanArray [PerkinElmer] (1)

Publication Date

2012 (132)
2013 (113)
2010 (110)
2011 (107)
2016 (105)
2015 (105)
2014 (100)
2008 (70)
2025 (47)
2009 (44)
2021 (40)
2026 (35)
2018 (30)
2019 (28)
2022 (26)
2007 (26)
2024 (25)
2023 (22)
2020 (20)
2017 (18)
2006 (7)
2005 (4)
2004 (3)

CHEBI ID

CHEBI:26271 (2)
CHEBI:27266 (2)
CHEBI:29016 (2)
CHEBI:6650 (2)
CHEBI:16865 (2)
CHEBI:18012 (2)
CHEBI:16449 (2)
CHEBI:30769 (2)
CHEBI:138900 (1)
CHEBI:23252 (1)
CHEBI:57746 (1)
CHEBI:58003 (1)
CHEBI:46960 (1)
CHEBI:233489 (1)
CHEBI:134435 (1)
CHEBI:58115 (1)
CHEBI:456215 (1)
CHEBI:72352 (1)
CHEBI:25682 (1)
CHEBI:49168 (1)
CHEBI:67040 (1)
CHEBI:57567 (1)
CHEBI:30830 (1)
CHEBI:17141 (1)
CHEBI:28918 (1)
CHEBI:1547 (1)
CHEBI:41941 (1)
CHEBI:17485 (1)
CHEBI:36090 (1)
CHEBI:17992 (1)

Metabolite Name

Oxidized glutathione (2)
Norepinephrine (2)
Homovanillic acid (2)
Uracil (2)
Thymine (2)
Quinolinic acid (2)
Orotic acid (2)
Citrulline (2)
2-Hydroxybutyric acid (2)
Nicotinic acid (2)
Putrescine (2)
Allantoin (2)
Serotonin (2)
Acetylcholine (2)
Choline (2)
Taurocholic acid (2)
Niacinamide (2)
Glutathione (2)
Fumaric acid (2)
Isocitric acid (2)
Cytosine (2)
Asymmetric dimethylarginine (2)
Adenine (2)
Uric acid (2)
Cytidine (2)
Hypoxanthine (2)
HexCer(d32:1) (1)
3-Dehydro-scyllo-inosose (1)
PE(31:1) (1)
Adenosine 5'-phosphate disodium (1)

First Public Date

2025 (39)
2014 (32)
2024 (23)
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2021 (12)
2019 (12)
2015 (12)
2022 (11)
2020 (11)
2023 (10)
2018 (9)
2017 (7)
2016 (2)
2013 (2)

Classification

viruses (1)

Study status

Completed (6)
Recruiting (4)
Not provided (3)
Terminated (2)
Active, not recruiting (2)

Study type

Transcription profiling by array (617)
RNA-seq of coding RNA (138)
ChIP-seq (72)
Comparative genomic hybridization by array (38)
RNA-seq of coding RNA from single cells (25)
Unknown experiment type (16)
Methylation profiling by array (12)
Methylation profiling by high throughput sequencing (12)
ChIP-chip by array (9)
ATAC-seq (7)
Other (7)
DNA-seq (7)
Transcription profiling by RT-PCR (6)
RNA-seq of non coding RNA (6)
Animal - High-throughput sequencing (5)
Genotyping by array (5)
Transcription profiling by SAGE (4)
High-throughput sequencing (4)
ChIP-chip by tiling array (3)
CLIP-seq (3)
MicroRNA profiling by array (3)
Animal - One-color microarray (2)
RNAi profiling by array (2)
ScATAC-seq (2)
Differential (1)
Human - Methylation microarray (1)
Animal - Single-cell sequencing (1)
Human - Single-cell sequencing (1)
Cell line - One-color microarray (1)
Transcription profiling by tiling array (1)

Release Date

2016 (199)
2021 (195)
2025 (189)
2022 (178)
2015 (171)
2012 (170)
2014 (165)
2013 (153)
2019 (150)
2023 (148)
2010 (139)
2020 (138)
2024 (134)
2011 (132)
2018 (115)
2008 (88)
2017 (82)
2009 (61)
2026 (37)
2007 (36)
2006 (10)
2005 (9)
2004 (6)
2002 (5)
2003 (3)
2000 (2)
1998 (1)

Lab affiliation

CRUK -CRUK Scotland nstitute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (2)
Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB) (2)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
CRUK -CRUK Scotland Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (1)
Département de biochimie Faculté de Médecine Université de Montréal (1)
Head of Analytical Biochemistry (1)
Head of Analytical Biochemistry, University of Groningen (1)
Head of Laboratory of Neuro-Oncology, Neurology, Clinical & Cancer Proteomics (1)
Michigan Center for Translational Pathology, University of Michigan (1)
OmicVision Biosciences ApS (1)
The Affiliated Hospital of Putian University (1)

Location

China (5)
Netherlands (4)
United Kingdom (2)
Japan (2)
Germany (2)
United States (2)
Singapore (1)
Israel (1)
Australia (1)

Keyword

Piecemeal polypectomy (1)
Piecemeal endoscopic mucosal resection (EMR) (1)
Endoscopic submucosal dissection (ESD) (1)
Endoscopic en-bloc resection (1)
AI system (1)
Guided Biopsy (1)
Colonoscope (1)
Mismatch repair (1)
Probe-based imaging of GI pre-malignant or malignant lesions (1)
Non-atrophic Gasrititis (1)
Immunohistochemistry (1)
Inoperable (1)
Mitomycins (1)
Mitomycin (1)
Locally advanced (1)
Confocal laser endomicroscopy (1)
Metastatic (1)

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Disruption of PPARg signaling results in mouse prostatic intraepithelial neoplasia (mPIN) involving active autophagy

Peroxisome proliferator-activated receptor-gamma (PPARg) regulates the interface between cellular lipid metabolism, redox status and organelle differentiation. Following conditional prostatic epithelial knockout of PPARg in mice we observed focal hyperplasia of the epithelium which developed to mous...

ORGANISM(S): Mus musculus

2010-05-18 | E-GEOD-13867 | biostudies-arrayexpress

Biomarkers for Cervical Cancer. iTRAQ Discovery.

We developed a discovery-validation mass-spectrometry based pipeline to identify a set of proteins that are regulated in serum of patients with cervical intraepithelial neoplasia (CIN) and squamous cell cervical cancer using isobaric Tags for Relative and Absolute Quantitation (iTRAQÂ®), label-free ...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-19 | MSV000079925 | MassIVE

Label-free quantitative proteomics of gastric high-grade intraepithelial neoplasia

Purpose: Early detection and diagnosis are the keys to improving the survival rate and reducing the fatality rate linked to gastric cancer. The precancerous lesion of gastric cancer is referred to as Gastric high-grade intraepithelial neoplasia (HGIN). Both sensitivity and specificity of current bio...

ORGANISM(S): Homo sapiens (Human)

2025-06-02 | PXD036991 | Pride

Transcription profiling by array of human prostate from patients with a previous diagnosis of Prostatic Intraepithelial Neoplasia and following consumption of high glucosinolate broccoli or peas to investigate interactions with the GSTM1 genotype

Twenty-two male volunteers aged 30-70 years with a previous diagnosis of Prostatic Intraepithelial Neoplasia (PIN) were recruited by a consultant urologist at Norfolk and Norwich University Hospital NHS Trust. Ethical approval for the trial was obtained from the Norfolk Research Ethics Committee (re...

ORGANISM(S): Homo sapiens

2008-07-16 | E-MEXP-1243 | biostudies-arrayexpress

LCM based proteomics of pancreatic intraepithelial neoplasia and adjacent normal tissues

Pancreatic intraepithelial neoplasia and adjacent normal tissues were isolated by laser capture microdissection and analyzed by 4D-DIA proteomics.

ORGANISM(S): Homo Sapiens

2024-09-21 | PXD056113 |

GNPS Comparable plasma lipid changes in patients with high-grade cervical intraepithelial neoplasia and patients with cervical cancer

Comparable plasma lipid changes in patients with high-grade cervical intraepithelial neoplasia and patients with cervical cancer

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2020-10-22 | MSV000086351 | GNPS

Transcription profiling of human vulvar epithelial neoplasia vs normal controls

In order to understand the molecular mechanism behind Vulvar Intraepithelial Neoplasia (VIN), we have analyzed the gene expression profile of VIN lesions in comparison to controls. Experiment Overall Design: Nine VIN and 10 control samples were collected. RNA of each sample was isolated and analyzed...

ORGANISM(S): Homo sapiens

2007-11-01 | E-GEOD-5563 | biostudies-arrayexpress

A constitutively activated form of the p110 beta isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice

The global gene expression profiles of ventral prostates of wild type mice and p110 beta transgenic mice. normal prostate vs. prostate cancer induced by the overexpression of the active allele of p110 beta

ORGANISM(S): Mus musculus

2010-06-08 | E-GEOD-21543 | biostudies-arrayexpress

Riboflavin deficiency regulates inflammation-associated genes in rat esophageal intraepithelial neoplasia

PRJNA436162 | ENA

Positioning of Necrotic Lobular Intraepithelial Neoplasias within the sequence of breast carcinoma progression

Lobular intraepithelial neoplasia grade 3 (LIN) is a recently recognized variant of intraepithelial lobular neoplasia of the breast composed of either uniform, generally small, cells (classic) with massive lobular distension, pleomorphic cells, signet-ring cells, or any cell type with necrosis. In ...

ORGANISM(S): Homo sapiens

2010-06-20 | E-GEOD-14803 | biostudies-arrayexpress

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