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ProteomicsInterspecific and Intraspecific Variation in Venom Proteomics, Composition, and Antivenom Efficacy of Thai Cobras (Naja spp.): Highlighting the Distinct Profile of the Newly Identified Naja fuxi.
Cobras (Naja spp.) account for a significant number of snakebite incidents in Thailand. The monocled cobra (Naja kaouthia) has historically been considered the only non-spitting species, but recent evidence indicates population-level diversification in central and southern regions. Additionally, a n...
ORGANISM(S): Naja sp. Trimeresurus 
2026-04-21 | PXD073641 | Pride
Geographical variation Neutralisation Immunoreactivity Cobra venom proteome Naja fuxi Enzyme assays 
ProteomicsIntraspecific Venom Variation between Tetrastichum brontispae strains
The venom apparatus is a conserved organ in parasitoid wasps that shows adaptations correlated with life-style diversification. Recent venom analyses from selected species reveal considerable complexity and high diversity in venom composition existing not only between closely related species but eve...
ORGANISM(S): Tetrastichus 
2018-11-06 | PXD004653 | Pride
Tetrastichus brontispae Venom Lable-free 
ProteomicsMolecular mechanisms underlying intraspecific variation in snake venom
Elucidating the molecular mechanisms underlying snake venom variability provides important clues for understanding how the biological functions of this powerful toxic arsenal evolve. We analyzed in detail individual transcripts and venom protein isoforms produced by five specimens of a venomous snak...
ORGANISM(S): Bothrops atrox 
2023-07-04 | PXD043541 | Pride
Plasticity Snake venom Toxin function Proteome Evolution Transcriptome 
ProteomicsSnake Venom LC/MSE - Post-transcriptional Mechanisms Contribute Little to Phenotypic Variation in Snake Venoms
Protein expression is a major link in the genotype-phenotype relationship, and processes affecting protein abundances, such as rates of transcription and translation, could contribute to phenotypic evolution if they generate heritable variation. Recent work has suggested that mRNA abundances do not ...
ORGANISM(S): Micrurus fulvius (Eastern coral snake) (Coluber fulvius) Sistrurus miliarius barbouri (Dusky pigmy rattlesnake) (Sistrurus barbouri) Crotalus horridus (Timber rattlesnake) Crotalus adamanteus (Eastern diamondback rattlesnake) Hypsiglena jani Sistrurus catenatus (massasauga) Agkistrodon contortrix Boiga irregularis (Brown tree snake) Micrurus tener (Texas coral snake) Agkistrodon piscivorus (cottonmouth) 
2015-11-09 | PXD002837 | Pride
Snake venom Lc/mse 
ProteomicsQualitative and quantitative analysis of Bothrops jararaca venom gland proteome
While cellular transcripts encode rich information that provide key features to understand the molecular basis of snake venom variation, their presence/ abundance does not necessary imply/correlate in the translation of a functional (protein) product. In this study we carried out an analysis of the ...
ORGANISM(S): Bothrops jararaca (Jararaca) (Bothrops jajaraca) 
2016-09-28 | PXD004186 | Pride
Venom gland proteome Snake venom proteome Bothrops jararaca Venom variability 
ProteomicsNorth vs. South: Ecoregion-Specific Variations of Venom Toxin Profiles and Functional Activities in Nigerian Bitis arietans and Naja nigricollis
Snakebite envenoming is a major yet neglected tropical disease in sub-Saharan Africa, where antivenom efficacy is critically limited by intraspecific venom variation shaped by local'eco-logical pressures. Nigeria’s sharply contrasting Sudan Savanna (North) and Lowland Rainforest (South) provide an i...
ORGANISM(S): Bitis arietans Naja nigricollis 
2026-06-01 | PXD073787 | Pride
Venom variation  bitis arietans  naja nigricollis  snakebite envenoming  geo-graphical venom phenotypes 
ProteomicsVenom Composition of Larval Stages of Tabanus autumanlis
Within the life cycle of many tabanids a purpose shift of venom usage occurs with larvae utilizing it for incapacitating invertebrate prey and female adults injecting their venom to promote blood feeding in vertebrates. While the venom of tabanid females has been investigated for a few species, the ...
ORGANISM(S): Tabanus autumnalis 
2026-09-14 | PXD073077 | Pride
Entomo-venomics Intraspecific venom variation Horse flies Toxins 
UnknownHighly Evolvable: Investigating Interspecific and Intraspecific Venom Variation in Taipans (Oxyuranus spp.) and Brown Snakes (Pseudonaja spp.).
Not available
S-EPMC9864820 | biostudies-literature
ProteomicsA developmental shift in venom toxin expression underpins a major prey switch in Australian Brown Snakes
Many animals undergo morphological, physiological, and behavioral changes over the course of their life history. It has been proposed that some of these developmental changes evolve in concert with shifts in ecology, but there are relatively few clear examples, and identifying the underlying molecul...
ORGANISM(S): Pseudonaja modesta Pseudonaja textilis Pseudonaja aspidorhyncha 
2026-04-13 | PXD063001 | Pride
ProteomicsConvergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps
Gene duplication, accompanied by modification of the expression and/or function of one of the duplicates under the action of positive selection, followed by further duplication to produce multigene families of toxins is a well-documented process in venomous animals. This evolutionary model has been ...
ORGANISM(S): Leptopilina boulardi Leptopilina heterotoma 
2023-06-09 | PXD041695 | Pride
Gene duplication Venom Evolution Positive selection Parasitoids Rhogap Ovarian calyx 
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