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MetabolomicsSuboxic DOM is bioavailable to surface prokaryotes in a simulated overturn of an oxygen minimum zone, Devil’s Hole, Bermuda
Oxygen minimum zones (OMZs) are expanding due to increased sea surface temperatures, subsequent increased oxygen demand through respiration, reduced oxygen solubility, and thermal stratification driven in part by anthropogenic climate change. Devil's Hole, Bermuda is a model ecosystem to study OMZ m...
2024-02-27 | MTBLS8122 | MetaboLights
MetabolomicsUntargeted metabolomic analysis in cats with naturally occurring inflammatory bowel disease and alimentary small cell lymphoma
Feline chronic enteropathy (CE) is a common gastrointestinal disorder in cats and mainly comprises inflammatory bowel disease (IBD) and small cell lymphoma (SCL). Differentiation between IBD and SCL can be diagnostically challenging. We characterized the fecal metabolome of 14 healthy cats and 22 ca...
2021-07-13 | MTBLS440 | MetaboLights
UnknownDose escalation to rash for erlotinib plus gemcitabine for metastatic pancreatic cancer: the phase II RACHEL study.
Not available
S-EPMC4260026 | biostudies-literature
Proteomicsbreast cancer mitochondria pulldown
pull-down of protein extracted from isolated mitochondria fraction
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD030730 | Pride
Cancer Mitochondria Pull-down 
TranscriptomicsIdentification of the teixobactin-induced CroRS regulon in Enterococcus faecalis using RNA-seq.
CroRS is a cell envelope stress response two-component system in the bacterial pathogen Enterococcus faecalis. Antimicrobial tolerance is the ability of an organism to survive, but not proliferate, upon antimicrobial challenge, and is a known precursor to the development of antimicrobial resistance....
ORGANISM(S): Enterococcus faecalis 
2023-09-22 | E-MTAB-12526 | biostudies-arrayexpress
TranscriptomicsRNA Expression Profiling of Human iPSC-Derived Cardiomyocytes in a Cardiac Hypertrophy Model [miRNA expression]
Cardiac hypertrophy is an independent risk factor for cardiovascular disease and heart failure. There is increasing evidence that microRNAs (miRNAs) play an important role in the regulation of messenger RNA (mRNA) and the pathogenesis of various cardiovascular diseases. However, the ability to compr...
ORGANISM(S): Homo sapiens 
2014-10-03 | E-GEOD-60292 | biostudies-arrayexpress
UnknownBiophysical characterization and solution structure of the cannulae-forming protein CanA from the hyperthermophilic archaeon Pyrodictium abyssi.
Not available
S-EPMC12326000 | biostudies-literature
ProteomicsSpecialised skin cancer library spectral library for use in data independent mass spectrometry
A specialised spectral ion reference library for use in data independent acquisition mass spectrometry applications for the purposes of skin specific research with a particular focus on melanoma and keratinocytic carcinoma
ORGANISM(S): Homo sapiens (Human) 
2021-08-23 | PXD025791 | Pride
Proteomics Skin Keratinocytic Carcinoma Melanoma Human 
MetabolomicsSmall molecule produced by Photorhabdus interferes with ubiquinone biosynthesis in Gram-negative bacteria

We report identification of 3,6-dihydroxy-1,2-benzisoxazole (DHB) in a screen of Photorhabdus and Xenorhabdus, whose symbiotic relationship with eukaryotic nematodes favors secondary metabolites that meet several requirements matching those for clinically useful antibiotics. DHB is produced by Ph...

2024-09-06 | MTBLS10720 | MetaboLights
Metabolomics1H NMR metabolite monitoring during the differentiation of human induced pluripotent stem cells provides new insights into the molecular events that regulate embryonic chondrogenesis
The integration of cell metabolism with signalling pathways, transcription factor networks and epigenetic mediators is critical in coordinating molecular and cellular events during embryogenesis. Induced pluripotent stem cells (IPSCs) are an established model for embryogenesis, germ layer specificat...
2023-05-24 | MTBLS4854 | MetaboLights
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