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ProteomicsMALT1 paracaspase controls cholesterol homeostasis in glioblastoma stem-like cells through lysosome proteome shaping
Glioblastoma stem-like cells (GSCs) compose a tumor-initiating and propagating-population, remarkably vulnerable to any variation in the stability and integrity of the endolysomal compartment. Previous work showed that the expression and activity of the paracaspase MALT1 control GSC viability via ly...
ORGANISM(S): Homo sapiens (Human) 
2025-01-16 | PXD040855 | Pride
Malt1 Srebp2 Niemann-pick type c1 Lysoip Glioblastoma Lysosomes Cholesterol 
UnknownMRI Apparent Diffusion Coefficient (ADC) as a Biomarker of Tumour Response: Imaging-Pathology Correlation in Patients with Hepatic Metastases from Colorectal Cancer (EORTC 1423).
Not available
S-EPMC10377224 | biostudies-literature
ProteomicsMALT1 paracaspase controls cholesterol homeostasis in glioblastoma stem-like cells through lysosome proteome shaping
Glioblastoma stem-like cells (GSCs) compose a tumor-initiating and propagating-population, remarkably vulnerable to any variation in the stability and integrity of the endolysomal compartment. Previous work showed that the expression and activity of the paracaspase MALT1 control GSC viability via ly...
ORGANISM(S): Homo sapiens (Human) 
2025-01-16 | PXD040862 | Pride
Malt1 Srebp2 Niemann-pick type c1 Lysoip Glioblastoma Lysosomes Cholesterol 
GenomicsWhole Genome Scan for Pancreatic Cancer Risk in the Pancreatic Cancer Cohort Consortium and Pancreatic Cancer Case-Control Consortium (PanScan)

Within the framework of the NCI-sponsored Cohort Consortium, investigators from 12 prospective epidemiologic cohorts formed the Pancreatic Cancer Cohort Consortium in 2006. This study, also known as "PanScan", is funded by the National Cancer Institute (NCI) and involves conducting a genome-w...

phs000206.v3.p2 | EGA
TranscriptomicsRecurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy [GPL6984]
STAG2 is a novel UBC tumor suppressor acting through mechanisms that are different from its role to prevent aneuploidy Gene copy number analyses of STAG2 in urinary bladder tumors. R values were extracted from beadstudio and normalised using the pounds method. Log R Ratios were calculated using an a...
ORGANISM(S): Homo sapiens 
2013-10-24 | E-GEOD-51589 | biostudies-arrayexpress
TranscriptomicsRecurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy [GPL6983]
STAG2 is a novel UBC tumor suppressor acting through mechanisms that are different from its role to prevent aneuploidy Gene copy number analyses of STAG2 in urinary bladder tumors. R values were extracted from beadstudio and normalised using the pounds method. Log R Ratios were calculated using an a...
ORGANISM(S): Homo sapiens 
2013-10-24 | E-GEOD-51640 | biostudies-arrayexpress
UnknownThe impact of a poverty reduction intervention on infant brain activity.
Not available
S-EPMC8812534 | biostudies-literature
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