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TranscriptomicsTranscription profiling of mouse wildtype and Myb Plt4/+ Pro B cells
A comparison of WT pro B cells to Myb Plt4/+ Pro B Cells
ORGANISM(S): Mus musculus 
2009-12-31 | E-TABM-690 | biostudies-arrayexpress
UnknownIntegrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures.
Not available
S-EPMC6414622 | biostudies-literature
ProteomicsQuantification of exercise-regulated ubiquitin-signalling
The maintenance of muscle function is extremely important for whole body health and exercise is essential to this process. The ubiquitin-proteasome system (UPS) is required for muscle adaptation following exercise but little is known about acute post-translational regulation and proteome remodelling...
ORGANISM(S): Homo sapiens (Human) 
2020-03-17 | PXD016158 | Pride
Proteomics Exercise Ubiquitin 
UnknownLong non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia.
Not available
S-EPMC6332539 | biostudies-literature
ProteomicsProteomic analysis of ischemic and dilated cardiomyopathy pre-mortem human hearts
Our understanding of heart failure (HF) has been provided by indirect surrogates, such as post-mortem histology, cardiovascular imaging, and molecular characterisation in vivo and in vitro, rather than directly in pre-mortem human cardiac tissue. Using our heart bank of pre-mortem hearts procured ac...
ORGANISM(S): Homo sapiens (Human) 
2020-05-01 | PXD018678 | Pride
Ischemic cardiomyopathy Myocardium Dilated cardiomyopathy 
ProteomicsProteomic analysis of NDUFS4 KO hearts
we performed whole heart proteomic analyses in both WT and NDUFS4 heart-specific cKO mice (n = 5 mice/group).
ORGANISM(S): Mus musculus (Mouse) 
2023-06-01 | PXD036399 | Pride
Ndufs4 
ProteomicsMultiplexed temporal quantification of the human plasma peptidome
The plasma peptidome contains the entire complement of low molecular weight endogenous peptides derived from secretion, protease activity and post-translational modifications and is a rich source of biomarkers and novel bioactives. To examine the utility of peptidomics we have examined the effects o...
ORGANISM(S): Homo sapiens (Human) 
2017-11-21 | PXD004781 | Pride
Peptidomics Exercise Peptidome Plasma 
ProteomicsOptimising sample preparation of the plasma peptidome
We further expanded on previous optimizations to isolate the plasma peptidome and compared various methods to maximize identifications with speed and ease. Previous studies have reported loss of polypeptides binding to high abundant proteins during depletion strategies. We hypothesized that rapid c...
ORGANISM(S): Homo sapiens (Human) 
2017-10-09 | PXD007191 | Pride
Peptidomics Plasma Sample preparation 
ProteomicsProteomic analysis of L6 myoblasts treated with C-terminal transgelin peptides
To investigate bioactivity of peptides identified in human plasma, we treated L6 myoblasts in vitro with a synthetic C-terminal peptide from TAGLN spanning amino acids 179-200, or a synthetic C-terminal peptide from TAGLN2 spanning amino acids 178-199 (1 µg/mL; 7 days), and compared the treatments t...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-11-21 | PXD007176 | Pride
Peptidomics Myoblasts Proteomics 
ProteomicsPhosphoproteomics of rodent exercise models
Exercise stimulates systemic and tissue-specific adaptations that protect against lifestyle related diseases including obesity and type 2 diabetes. Exercise places high mechanical and energetic demands on contracting skeletal muscle, which require finely-tuned protein post-translational modification...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2019-07-22 | PXD010452 | Pride
Skeletal muscle Signal transduction Exercise Phosphoproteomics 
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