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TranscriptomicsBovine Day 15 Extra-embryonic membrane (EEM): Male and Female Control vs. Male and Female CSF2 Methylation
We aimed to study the effects of CSF2 treatment on the methylome of the Day 15 female and male embryo. Methylomic profiling of bovine extra-embryonic membrane at Day 15 post-insemination produced by IVF. Oocytes were matured and fertilized in vitro using a single Holstein bull. After 5 days in vitro...
ORGANISM(S): Bos taurus 
2014-10-01 | E-GEOD-55873 | biostudies-arrayexpress
MetabolomicsSubcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages
Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, remains the world's deadliest infectious disease. Sterilizing chemotherapy requires at least 6 months of multidrug therapy. Difficulty visualizing the subcellular localization of antibiotics in infected host cells means t...
2020-12-07 | MTBLS959 | MetaboLights
UnknownThe small G-protein RalA promotes progression and metastasis of triple-negative breast cancer.
Not available
S-EPMC8196523 | biostudies-literature
TranscriptomicsCSF2 x gender interactions on the transcriptome of Day 15 bovine extra-embryonic membrane
We aimed to study the effects of CSF2 treatment on the transcriptome of the Day 15 female and male embryo. Within the raw files, channel 1= Cy3 and channel 2= Cy5 Transcriptional profiling of bovine extra-embryonic membrane at Day 15 post-insemination produced by IVF. Oocytes were matured and ferti...
ORGANISM(S): Bos taurus 
2014-10-01 | E-GEOD-55364 | biostudies-arrayexpress
ProteomicsThe salivary gland proteome of root-galling grape phylloxera (Daktulosphaira vitifoliae Fitch) feeding on Vitis spp.
Herbivory plant-parasite interactions depend on the delivery of effector molecules by the invading insect species. Sedentary gall forming insects, such as grape phylloxera (Daktulosphaira vitifoliae FITCH, Phylloxeridae) secrete multiple effectors into host plant tissues that alter host cellular fun...
ORGANISM(S): Daktulosphaira vitifoliae 
2020-07-22 | PXD014663 | Pride
Daktulosphaira vitifoliae Proteomics Salivary gland Phylloxera Effectors 
TranscriptomicsDifferential Streptococcus agalactiae gene expression in human blood according to the blood donors
In the present investigation, we conducted a bacterial transcriptome dynamics analysis during GBS incubation with human blood. We observed large modification in the expression of numerous genes, but GBS transcriptome was different with the blood of one donor. More genes were up-regulated and less do...
ORGANISM(S): Streptococcus agalactiae 
2009-06-01 | E-GEOD-12201 | biostudies-arrayexpress
TranscriptomicsInduction of adaptive changes in the Streptococcus agalactiae transcriptome by human blood
In the present investigation, we conducted a bacterial transcriptome dynamics analysis during GBS incubation with human blood. We observed a large modification in the expression of genes involved in transcriptional regulation and in the metabolism of carbohydrates, purins/pyrimidins and inorganic io...
ORGANISM(S): Streptococcus agalactiae 
2008-10-31 | E-GEOD-11705 | biostudies-arrayexpress
TranscriptomicsComparison of L-carnitine treated day 6 in vivo bovine embryos to controls, in both the Jersey and Holstein breeds.
The decreased rate of pregnancy obtained in cattle using frozen in vitro embryos compared to in vivo embryos has been associated with over-accumulation of intracellular lipid, which causes cell damage during cryopreservation. It is believed that the higher lipid content of blastomeres of bovine embr...
ORGANISM(S): Bos taurus 
2014-10-23 | E-GEOD-62595 | biostudies-arrayexpress
UnknownPyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair.
Not available
S-EPMC6218445 | biostudies-literature
TranscriptomicsThe Complete Genome of a Single Individual by Massively Parallel DNA Sequencing
The association of genetic variation with disease and drug response, together with improvements in nucleic acids technologies, has given great optimism for the impact of 'genomic medicine'. However, the formidable size of the diploid human genome has prevented the routine application of sequencing ...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10668 | biostudies-arrayexpress
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