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TranscriptomicsUnexpected complexity of the Escherichia coli K-12 transcriptome architecture revealed by single nucleotide resolution RNA sequencing
To investigate the architecture of the E. coli K-12 transcriptome, we used two RNA-Seq technologies to analyze strand-specific transcription at single-nucleotide resolution. We analyzed the data by using an organizational schema to annotate the promoters and terminators that define transcription uni...
ORGANISM(S): Escherichia coli K-12 
2014-07-08 | E-GEOD-52059 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human erythroleukemia cell line K-562 with H3K4me2, H3K4me3, H3ac, H4ac, Histone H2B and Histone H3 antibodies using an ENCODE array
ENCODE ChIP-chip study using human myelogenous leukemia cell line K-562 and anti histone H3K4me2 (Abcam; ab7766); H3K4me3 (Abcam; ab8580); H3ac (Upstate; 06-599); H4ac (Upstate; 06-866); Histone H2B (Abcam: ab1790) and Histone H3 (Abcam: ab1791) antibodies. Each antibody experiment was conducted in ...
ORGANISM(S): Homo sapiens 
2006-09-01 | E-TABM-140 | biostudies-arrayexpress
ProteomicsUbiquitin-mediated modulation of necroptotic effector MLKL
We aimed to identify lysine (K) residues that are endogenously ubiquitylated upon TNF-induced necroptosis. To this end, we used a quantitative mass spectrometry-based approach. Briefly, MDFs were treated with TSZ or left untreated and protein lysates were digested with trypsin into peptides. Ubiquit...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-13 | PXD018857 | Pride
Ubiquitin Tmt Cancer Mlkl Mouse Msms 
TranscriptomicsDefective K-Ras Oncoproteins Initiate Cancer In Vivo and Evolve to Overcome Impaired Effector Binding
The oncogenic proteins expressed in human cancer cells are exceedingly difficult targets for drug discovery due to intrinsic properties of the Ras GTPase switch. As a result, recent efforts have largely focused on inhibiting Ras-regulated kinase effector cascades, particularly the Raf/MEK/ERK and PI...
ORGANISM(S): Mus musculus 
2011-09-30 | E-GEOD-28687 | biostudies-arrayexpress
UnknownAssociation of vitamin K with cognitive decline and neuropathology in community-dwelling older persons.
Not available
S-EPMC9019903 | biostudies-literature
TranscriptomicsSNP data from human fibroblasts and induced Pluripotent Stem cells from Parkinson's Disease patients
We have generated human induced Pluripotent Stem cells (hiPSc) from Parkinson's Disease patients, using retrovirus-mediated delivery of reprogramming factors. hiPSc lines have been screened using SNP array to assess chromosomal stability (alongside the fibroblast lines from which they derived), and ...
ORGANISM(S): Homo sapiens 
2013-12-18 | E-GEOD-53425 | biostudies-arrayexpress
UnknownCharacterization of a K+-induced conformational switch in a human telomeric DNA oligonucleotide using 2-aminopurine fluorescence.
Not available
S-EPMC2803354 | biostudies-literature
UnknownK-edge Subtraction Computed Tomography with a Compact Synchrotron X-ray Source.
Not available
S-EPMC6746727 | biostudies-literature
UnknownThe impact of APOE4 on neurological symptoms after exposure to K. brevis neurotoxin.
Not available
S-EPMC12022920 | biostudies-literature
ProteomicsCerebrospinal fluid markers to distinguish bacterial meningitis from cerebral malaria in children
Clinically distinguishing acute bacterial meningitis from cerebral malaria, both of which are important causes of acute non-traumatic coma associated with morbidity and mortality among paediatric hospital admissions in malaria endemic areas of Africa, is challenging. Few hospitals have diagnostic ca...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-24 | MSV000080979 | MassIVE
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