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MetabolomicsLC-MS analysis of faecal extracts obtained during colorectal cancer resectional surgery

A prospective observational pilot study from right-sided colorectal cancer (RCRC) patients was performed at Imperial College London NHS Trust, UK. Treatment naïve patients undergoing elective resectional surgery for primary RCRCs were recruited. Fresh intra-luminal fecal samples were obtained at ...

2025-07-11 | MTBLS11775 | MetaboLights
ProteomicsA novel translocon for biogenesis of multi-pass membrane proteins
A novel 370 kDa translocon comprising Sec61 and five accessory factors acting co-translationally with ribosomes to fold and insert multi-pass membrane proteins was identified, purified and analyzed structurally by single particle cryo-EM and cross-linking mass spectrometry. The purified ribosome-tr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-08 | MSV000084065 | MassIVE
UnknownDoxepin rinse versus placebo in the treatment of acute oral mucositis pain in patients receiving head and neck radiotherapy with or without chemotherapy: a phase III, randomized, double-blind trial (NCCTG-N09C6 [Alliance]).
Not available
S-EPMC4026580 | biostudies-literature
MetabolomicsMetabolic phenotyping of ex-vivo breast samples by DESI mass spectrometry imaging
This study involves the analysis of surgically resected samples from patients undergoing breast surgery. The samples published here have been used as part of the publication by [1], and all experimental details can be found within. Desorption electrospray ionisation mass spectrometry imaging (DESI M...
2016-04-28 | MTBLS273 | MetaboLights
GenomicsRING1B calibrated ChIP-seq (cChIPseq) datasets for control mESCs and an Scc1-AID auxin-inducible degron.
We examined 3D chromatin structure in the absence of cohesin (Scc1-AID auxin-inducible degron) and a control line (E14-Tir1) and found that PRC1 core promoter component RING1B was one of the most enriched proteins. Hence, we performed calibrated ChIP-seq experiments on the control (E14-Tir1) and the...
ORGANISM(S): Mus musculus 
2020-01-23 | E-MTAB-7817 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae IFO 0233 diploid strain sampled at multiple time point to investigate genome wide oscillations
In order to test the idea that the cell is an attractor and to examine in detail the connectivity relationships among genes, it was essential to have a very reproducible and precise biological system. Oscillations in respiratory activity in budding yeast and other organisms have been known for many...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-12 | E-GEOD-2583 | biostudies-arrayexpress
UnknownWDR82-Mediated H3K4me3 Is Associated with Tumor Proliferation and Therapeutic Efficacy in Pediatric High-Grade Gliomas.
Not available
S-EPMC10340597 | biostudies-literature
ProteomicsTargeted degradation of extracellular mitochondrial aspartyl-tRNA synthetase modulates immune responses in bacterial pneumonia
The severity of bacterial pneumonia can be worsened by impaired innate immunity resulting in ineffective pathogen clearance. Here We describe a mitochondrial protein, aspartyl-tRNA synthetase (DARS2), which is released in circulation during bacterial pneumonia in humans and displays intrinsic innate...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD050224 | Pride
Inflammation Pneumonia Dars2 
TranscriptomicsTranscription profiling of human growth plate chondrocytes were isolated from the distal femoral growth plate from 3 different adolescents undergoing epiphysiodesis
Human growth plate chondrocytes were isolated from the distal femoral growth plate from 3 different adolescents undergoing epiphysiodesis. Cell were isolated and grown in monolayers, long term, in 20% serum. Cells were replated and cultured 48 h in 0.5% serum.
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1278 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human growth plate chrondrocytes grown in monolayer, 0.5 vs. 20% serum
Human growth plate chondrocytes were isolated from the distal femoral growth plate from a single adolescent undergoing epiphysiodesis. Cell were isolated and grown in monolayers, long term. Cells were replated and cultured in 0.5% or 20% serum.
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1277 | biostudies-arrayexpress
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