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TranscriptomicsExpression data from Th2 cell of ECM1 KO mice vs WT mice
CD4+ helper T cells are critical for immunological response. Th2 cells, a subset of CD4+ helper T cells, are responsible for asthma and other immune diseases. We found a Th2 secreted protein, ExtraCellular Matrix protein 1 (ECM1), which is highly induced by classic IL-4 signaling pathway during help...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-19707 | biostudies-arrayexpress
ProteomicsUSP20 promotes T-ALL evolution by deubiquitinating modified HIF1A
Qualitative analysis of proteome is to study the types and quantities of proteome identified by samples under different conditions, and to perform functional analysis of the identified proteins, so as to provide reference information for quantitative and modification analysis of high-throughput prot...
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD053080 | Pride
Usp20 Hif1a 
UnknownEtoposide activates CD8<sup>+</sup> T cell anti-tumor immunity in osteosarcoma through MHC I upregulation via tumor-secreted IL-33 mediated signaling.
Not available
S-EPMC12718598 | biostudies-literature
UnknownAltered bile acids profile is a risk factor for hyperandrogenism in lean women with PCOS: a case control study.
Not available
S-EPMC11528117 | biostudies-literature
UnknownCD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells.
Not available
S-EPMC10439278 | biostudies-literature
UnknownSuper-Enhancer-Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T-ALL Cell Growth and Survival.
Not available
S-EPMC11714186 | biostudies-literature
UnknownVCP downstream metabolite glycerol-3-phosphate (G3P) inhibits CD8<sup>+</sup>T cells function in the HCC microenvironment.
Not available
S-EPMC11758394 | biostudies-literature
MetabolomicsMechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Zhuyu pill (ZYP) is a traditional Chinese medicine prescription composed of two drugs, Coptis chinensis Franch. and Tetradium ruticarpum (A. Jussieu) T. G. Hartley, and is commonly used in the clinical treatment of diseases of the digestive system. However, the mechanism underly...

2022-11-02 | MTBLS4980 | MetaboLights
ProteomicsComparative proteomic analysis revealed complex responses to classical/novel duck reovirus infections in the spleen cells of Cairna moschata
Duck reovirus (DRV), a member of the genus Orthoreovirus in the family Reoviridae, was first isolated from Muscovy ducks. The disease associated with DRV causes great economic losses to the duck industry. However, the responses of duck (Cairna moschata) to the classical/novel DRV (C/NDRV) infections...
ORGANISM(S): Cairina moschata 
2020-08-24 | PXD009703 | Pride
Cairna moschata  differential expressed protein  duck reovirus  proteome  serine protease  spleen 
UnknownTranscription factor NFAT5 contributes to the glycolytic phenotype rewiring and pancreatic cancer progression via transcription of PGK1.
Not available
S-EPMC6906509 | biostudies-literature
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