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ProteomicsThe plasma proteins from human multiple myeloma was enriched by lectin AANL6 and identified by LC-MS/MS
Lectin is widely used to enrich glycoconjugates carrying glycans and to identify the abnormal glycosylated proteins in tumor with mass spectrometry, which is a useful tool for cancer diagnosis and prognosis monitoring. In our previously reported, we identified a novel lectin AANL from Agrocybe aeger...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD027111 | Pride
Lectin aanl6 Mm Human Plasma Lc-ms/ms 
ProteomicsProteomics analysis of differentially expressed proteins in lung cancer H157 cells after overexpression of AACT with data‐independent acquisition mass spectrometry
H157 cells transfected with vector and overexpressed AACT plasmids were treated and used for MS detection. The MS data were acquired using an Orbitrap Exploris 480 Mass Spectrometer coupled with an EASY-NLC 1200 liquid phase LC-MS system. DIA raw data files were analyzed by DIA-NN software. The diff...
ORGANISM(S): Homo sapiens (Human) 
2023-07-18 | PXD036119 | Pride
Aact Proteomics Overexpression Dia Lung cancer 
ProteomicsIdentification of differentially expressed proteins in lung cancer H157 cells after nanocomposite AANL-SeNPs treatment with DIA-MS detection
H157 cells were treated with nanocomposite AANL-SeNPs and harvested for mass spectrometry detection. The mass spectrum data were obtained by timsTOF Pro combined with UltiMate 3000 RSLCnano liquid chromatograph system. DIA-NN software is used to analyze DIA original data files. The differentially ex...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD044000 | Pride
Lung cancer Proteomics Dia-ms Aanl-senps H157 
MetabolomicsIntegrated omics analysis reveals the alteration of gut microbiota and fecal metabolites in Cervus elaphus kansuensis
The gut microbiota is the largest and most complex microecosystem in animals. It is influenced by the host's dietary habits and living environment, and its composition and diversity play irreplaceable roles in animal nutrient metabolism, immunity, and adaptation to the environment. Although the gut ...
2024-08-08 | MTBLS6121 | MetaboLights
ProteomicsIntegrative analyses of antler cartilage transcriptome and pro-teome of Gansu red deer (Cervus elaphus kansuensis) at different growth stages
The velvet antler is a unique model for cancer and regeneration research due to its periodic re-generation and rapid growth. Antler growth is mainly triggered by the growth center located in its tip, which consists of velvet skin, mesenchyme and cartilage. Among them, cartilage accounts for most of ...
ORGANISM(S): Cervus elaphus kansuensis 
2022-05-20 | PXD032668 | Pride
Cervus elaphus kansuensis  endochondral ossification  rapid growth   histogenesis  multi-omics 
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