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To decipher the protective mechanisms underlying microglia specific heterozygous TAK1 deficiency in rd10 mouse model of retinitis pigmentosa, we analyzed the retinal proteomic profiles of normal C57BL/6J mice, tamoxifen-treated Cx3cr1CreER/+;Tak1fl/+, vehicle-treated rd10;Cx3cr1CreER/+;Tak1fl/+, and...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-17 | PXD061300 | Pride
Shiga toxin type 2 (Stx2) is the main virulence factor produced by Stx-producing Escherichia coli (STEC) responsible for hemorrhagic colitis and the life-threatening sequela hemolytic uremic syndrome.
ORGANISM(S): Homo Sapiens 
2022-11-21 | PXD038256 |
The goal is to identify regulatory RNAs that regulate the p53 signaling pathway in embryonic stem (ES) cells. p53+/+ mES cells and p53-/- mES cells were untreated or treated with 0.5 uM Adriamycin for 8 hours. Total RNA was extracted and subject to RNAseq.
ORGANISM(S): Mus musculus 

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

Sepsis is often a cause of mortality in patients admitted to the intensive care unit. Notably, the heart is the organ most susceptible to the impact of sepsis.Mice injected intraperitoneally with LPS solution (20 mg/kg) were designated as the sepsis experimental group, while those injected intraperi...
ORGANISM(S): Mus Musculus 
2024-12-24 | PXD059227 |
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