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MetabolomicsUntargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights
UnknownTracking Ovine Pulmonary Adenocarcinoma Development Using an Experimental Jaagsiekte Sheep Retrovirus Infection Model
Not available
S-EPMC11353984 | biostudies-literature
TranscriptomicsHuman CD4+ T-cell transcriptome in early arthritis
An exploration of the peripheral blood CD4+ T-cell transcriptome of early arthritis clinic attendees, seeking novel diagnostic tools and pathophysiological insights. Ex-vivo CD4+ T-cell RNA was obtained following first early arthritis clinic attendance from 173 patients. Four diagnostic categories ...
ORGANISM(S): Homo sapiens 
2012-03-03 | E-GEOD-20098 | biostudies-arrayexpress
ProteomicsCcr4-Not ubiquitin ligase signaling regulates ribosomal protein homeostasis and inhibits 40S ribosomal autophagy
The Ccr4-Not complex containing the Not4 ubiquitin ligase regulates gene transcription and mRNA decay, yet it also has poorly defined roles in translation, proteostasis, and endolysosomal-dependent nutrient signaling. To define how Ccr4-Not mediated ubiquitin signaling regulates these additional pro...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-10-17 | PXD044420 | Pride
Autophagy Endolysomal Ribosome Ccr4-not Not4 
UnknownHead and neck cancer N-glycome traits are cell line and HPV status-dependent.
Not available
S-EPMC9712327 | biostudies-literature
TranscriptomicsMolecular Mapping of Keratinocyte Differentiation by Functional Gene Expression Profiling
Our goal was to establish a robust and reliable platform for the mapping of gene expression changes occurring during the process of keratinocyte differentiation. We hypothesized that a functional gene expression profiling approach capable of identifying the program of gene expression over time would...
ORGANISM(S): Homo sapiens 
2013-12-15 | E-GEOD-26688 | biostudies-arrayexpress
ProteomicsAutomated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-um spatial resolution
Imaging mass spectrometry is a powerful emerging tool for mapping the spatial distribution of biomolecules across tissue surfaces. Here the authors showcase an automated technology for deep proteome imaging that utilizes ultrasensitive microfluidics and a mass spectrometry workflow to analyze tissue...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-10-04 | MSV000084421 | MassIVE
ProteomicsRaw data for the characterization of a Pseudomonas putida malonyl-ACP decarboxylase
Raw data for top down LCMS for detecting modifications on recombinant proteins, and GCMS for fatty acid methyl ester analysis. Sample nomenclature is summarized in the Powerpoint and PDF files. Details of experiments are given in the associated manuscript.
ORGANISM(S): Pseudomonas Putida Kt2440 (ncbitaxon:160488) 
MSV000090294 | MassIVE
MetabolomicsRepurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
2021-10-06 | MTBLS2166 | MetaboLights
UnknownPhase II Study of the Efficacy and Safety of Pembrolizumab for Relapsed/Refractory Classic Hodgkin Lymphoma.
Not available
S-EPMC5791843 | biostudies-literature
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