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UnknownValosin-containing Protein is Cargo in Amyloid Precursor Protein Extracellular Vesicles.
Not available
S-EPMC11785032 | biostudies-literature
ProteomicsMALT1 paracaspase controls cholesterol homeostasis in glioblastoma stem-like cells through lysosome proteome shaping
Glioblastoma stem-like cells (GSCs) compose a tumor-initiating and propagating-population, remarkably vulnerable to any variation in the stability and integrity of the endolysomal compartment. Previous work showed that the expression and activity of the paracaspase MALT1 control GSC viability via ly...
ORGANISM(S): Homo sapiens (Human) 
2025-01-16 | PXD040855 | Pride
Malt1 Srebp2 Niemann-pick type c1 Lysoip Glioblastoma Lysosomes Cholesterol 
ProteomicsMALT1 paracaspase controls cholesterol homeostasis in glioblastoma stem-like cells through lysosome proteome shaping
Glioblastoma stem-like cells (GSCs) compose a tumor-initiating and propagating-population, remarkably vulnerable to any variation in the stability and integrity of the endolysomal compartment. Previous work showed that the expression and activity of the paracaspase MALT1 control GSC viability via ly...
ORGANISM(S): Homo sapiens (Human) 
2025-01-16 | PXD040862 | Pride
Malt1 Srebp2 Niemann-pick type c1 Lysoip Glioblastoma Lysosomes Cholesterol 
UnknownOrganization of Presynaptic Autophagy-Related Processes.
Not available
S-EPMC8968026 | biostudies-literature
TranscriptomicsExpression data of CD107aLow and CD107aHigh cells isolated from human adipose tissue
The tunica adventitia of vessels within adipose tissue (AT) represents a heterogenous microanatomical niche for multipotent mesenchymal precursor cells. To investigate this heterogeneity, cell surface antibody array among CD34+ human adventicytes identified 13 novel antigens enriched within perivasc...
ORGANISM(S): Homo sapiens 
2020-10-06 | GSE148519 | GEO
ProteomicsCcr4-Not ubiquitin ligase signaling regulates ribosomal protein homeostasis and inhibits 40S ribosomal autophagy
The Ccr4-Not complex containing the Not4 ubiquitin ligase regulates gene transcription and mRNA decay, yet it also has poorly defined roles in translation, proteostasis, and endolysosomal-dependent nutrient signaling. To define how Ccr4-Not mediated ubiquitin signaling regulates these additional pro...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-10-17 | PXD044420 | Pride
Autophagy Endolysomal Ribosome Ccr4-not Not4 
GenomicsExpression data of CD107aLow and CD107aHigh cells isolated from human adipose tissue
Expression data of CD107aLow and CD107aHigh cells isolated from human adipose tissue
PRJNA624864 | ENA
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