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TranscriptomicsSystems Toxicology Identifies Mechanistic Impacts of 2-amino-4,6-dinitrotoluene (2-ADNT) Exposure in Northern Bobwhite
A systems toxicology investigation comparing and integrating transcriptomic and proteomic results was conducted to pursue a holistic understanding of the effects of the explosives degradation product 2-amino-4,6-dinitrotoluene (2A-DNT) dosing on the health of the wildlife bird model, Northern bobwhi...
ORGANISM(S): Colinus virginianus 
2015-07-01 | E-GEOD-59910 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights
TranscriptomicsTranscription profiling of Drosophila developmental time series
Michelle N. Arbeitman, Eileen E. M. Furlong, Farhad Imam, Eric Johnson, Brian H. Null, Bruce S. Baker, Mark A. Krasnow, Matthew P. Scott, Ronald W. Davis and Kevin P. White. Gene Expression During the Life Cycle of Drosophila melanogaster, Science, 297: 2270-2275, 2002. This work can be accessed fro...
ORGANISM(S): Drosophila melanogaster 
2004-11-06 | E-FLYC-6 | biostudies-arrayexpress
ProteomicsAnalysis of Brain Protein Stability Changes in Mouse Models of Normal Aging and a Synucleinopathy Reveals Age- and Disease-Related Differences
The lack of appropriate protein biomarkers makes the early detection of Parkinson’s disease (PD) challenging, and it thwarts efforts to develop drug therapies for this incurable disease. Thus, new approaches are needed for biomarker discovery and for better understanding the molecular basis of PD p...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-19 | PXD016985 | Pride
Brain Mouse Parkinson's disease 
UnknownValuing the Diversity of Research Methods to Advance Nutrition Science.
Not available
S-EPMC9340992 | biostudies-literature
ProteomicsAssessing protein sequence database suitability using de novo sequencing
The analysis of samples from unsequenced and/or understudied species as well as samples where the proteome is derived from multiple organisms poses two key questions. The first is whether the proteomic data obtained from an unusual sample type even contains peptide tandem mass spectra. The second ...
ORGANISM(S): glacier metagenome Hydrolagus colliei Diaphorina citri (Asian citrus psyllid) Homo sapiens (Human) marine metagenome Ursus deningeri Caenorhabditis elegans Leucoraja erinacea 
2019-11-20 | PXD015083 | Pride
Fasta Proteomics Metaproteomics 
UnknownHIV Prevention for Black Heterosexual Men: The Barbershop Talk with Brothers Cluster Randomized Trial.
Not available
S-EPMC6611102 | biostudies-literature
UnknownPhase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoprotein.
Not available
S-EPMC3164245 | biostudies-literature
UnknownThe Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging.
Not available
S-EPMC12353841 | biostudies-literature
UnknownDifferential Item Functioning and Clinical Utility of the Subjective Memory Complaints Questionnaire in a Multi-Ethnic Cohort.
Not available
S-EPMC11930848 | biostudies-literature
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