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UnknownImproving quality of care and long-term health outcomes through continuity of care with the use of an electronic or paper patient-held portable health file (COMMUNICATE): study protocol for a randomized controlled trial.
Not available
S-EPMC4473843 | biostudies-literature
UnknownPharmacodynamics of vancomycin for CoNS infection: experimental basis for optimal use of vancomycin in neonates.
Not available
S-EPMC4790623 | biostudies-literature
ProteomicsProteome and PTMs analyses of mammary CAFs
To understand the molecular mechanisms that underpin pro-tumourigenic functions of cancer-associated fibroblasts (CAFs) we compared the proteome, acetylome, phosphoproteome of human immortalised breast cancer CAFs with those of the normal mammary fibroblasts that they were generated from. Based on t...
ORGANISM(S): Homo sapiens (Human) 
2022-04-10 | PXD018343 | Pride
Human Breast cancer Acetylome Epigenetics Phosphoproteome Cancer-associated fibroblasts Proteome 
Metabolomics1H NMR Urinary Metabolomic Analysis in Older Adults after Hip Fracture Surgery May Provide Valuable Information for Patient Profiling-A Preliminary Investigation
In these times of precision and personalized medicine, profiling patients to identify their needs is crucial to providing the best and most cost-effective treatment. In this study, we used urine metabolomics to explore the characterization of older adults with hip fractures and to explore the foreca...
2022-10-31 | MTBLS2903 | MetaboLights
MetabolomicsCommon Metabolic Pathways Implicated in Resistance to Chemotherapy Point to a Key Mitochondrial Role in Breast Cancer
Cancer cells are known to reprogram their metabolism to adapt to adverse conditions dictated by tumor growth and microenvironment. A subtype of cancer cells with stem-like properties, known as cancer stem cells (CSC), is thought to be responsible for tumor recurrence. In this study, we demonstrated ...
2019-08-19 | MTBLS678 | MetaboLights
TranscriptomicsTranscriptional Profiling in Non-Human Primates Infected With Lassa Virus to Understand the Immune Response to Lassa Infection
Lassa fever virus (LASV) is a significant human pathogen that is endemic to several countries in West Africa. Infection with Lassa leads to the development of hemorrhagic fever in a significant number of public health cases and it is considered a potential bioweapon. Little is known about the compl...
ORGANISM(S): Macaca fascicularis 
2013-06-18 | E-GEOD-41752 | biostudies-arrayexpress
MetabolomicsEnvironmental Chemical Diethylhexyl Phthalate Alters Intestinal Microbiota Community Structure and Metabolite Profile in Mice
Exposure to environmental chemicals during windows of development is a potentially contributing factor in gut microbiota dysbiosis, and linked to chronic diseases and developmental disorders. We used a community-level model of microbiota metabolism to investigate the effects of diethylhexyl phthalat...
2022-01-17 | MTBLS861 | MetaboLights
TranscriptomicsTranscriptome of non-involved lung parenchyma from smoker lung adenocarcinoma patients from Milan, Italy.
Scientific evidence indicates that genetic factors may contribute to differences in lung cancer risk for individuals with similar levels of tobacco exposure, which is the main environmental risk factor of lung cancer. Moreover, lung cancer patients show large differences in clinical staging and surv...
ORGANISM(S): Homo sapiens 
2016-01-20 | E-GEOD-71181 | biostudies-arrayexpress
UnknownHealth and wellbeing of people with intellectual disability in New South Wales, Australia: a data linkage cohort.
Not available
S-EPMC6773320 | biostudies-literature
ProteomicsProteomic analysis of ECM-enriched fraction of breast xenograft and skin tissue from mice injected with 13C-glutamine
Elevated production of collagen-rich extracellular matrix (ECM) is a hallmark of cancer associated fibroblasts (CAFs) and a central driver of cancer aggressiveness. How to target ECM production to oppose cancer is yet unclear, since targeting CAFs has been shown to restrain but also promote cancer p...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-31 | PXD024746 | Pride
Collagen Xenograft tumour of mcf10dcis.com Breast cancer 
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