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TranscriptomicsExpression data from primary human keratinocytes exposed to cytokines in vitro (IL-4, IL-13, IL-17A, IFN-alpha, IFN-gamma, TNF)
The clinical features of psoriasis, characterized by sharply demarcated scaly erythematous plaques, are typically so distinctive that a diagnosis can easily be made on these grounds alone. However, there is great variability in treatment response between individual patients, and this may reflect het...
ORGANISM(S): Homo sapiens 
2012-03-07 | E-GEOD-36287 | biostudies-arrayexpress
TranscriptomicsExpression data from tail skin in young (5 months) and old (30 months) CB6F1 mice
Background: Skin aging is associated with intrinsic processes that compromise structure of the extracellular matrix while promoting loss of functional and regenerative capacity. These processes are accompanied by a large-scale shift in gene expression, but underlying mechanisms are not understood an...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-35322 | biostudies-arrayexpress
TranscriptomicsGene expression in psoriasis lesions and uninvolved skin
Psoriasis is a chronic inflammatory skin disease characterized by marked proliferation of keratinocytes leading to pronounced epidermal hyperplasia, elongation of rete ridges and hyperkeratosis. The most common form of psoriasis, chronic plaque psoriasis (Psoriasis vulgaris), involves relatively sta...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-50790 | biostudies-arrayexpress
UnknownQuality of life in MAP.3 (Mammary Prevention 3): a randomized, placebo-controlled trial evaluating exemestane for prevention of breast cancer.
Not available
S-EPMC4879707 | biostudies-literature
TranscriptomicsReconstituted human epidermis cultures treated with IL-1 family cytokines for 24 hours.
Analysis of stratified epidermal cultures treated with IL-1a, IL-1F5, IL-1F6, IL-1F8 and IL-1F9 to determine the effects of these cytokines at 24h. Results provide insight into the role of IL-1 family cytokines in the pathogenesis of psoriasis. 16 samples. 2 untreated controls, 14 cytokine treated
ORGANISM(S): Homo sapiens 
2010-11-17 | E-GEOD-25400 | biostudies-arrayexpress
TranscriptomicsDevelopment and Independent Validation of a Molecular Subtype in High Grade Serous Ovarian Cancer using Formalin Fixed Paraffin Embedded Tissue, Training set
High Grade Serous Ovarian Cancer (HGSOC) is a histopathological diagnosis and may represent multiple diseases at a molecular level. We investigated whether distinct molecular subgroups may influence treatment choice. The accompanying validation set of data has also been deposited in ArrayExpress und...
ORGANISM(S): Homo sapiens 
2020-12-21 | E-MTAB-2562 | biostudies-arrayexpress
UnknownObservations of volatile organic and sulfur compounds in ambient air and health risk assessment near a paper mill in rural Idaho, U. S. A.
Not available
S-EPMC7644087 | biostudies-literature
TranscriptomicsDevelopment and Independent Validation of a Molecular Subtype in High Grade Serous Ovarian Cancer using Formalin Fixed Paraffin Embedded Tissue, Validation set
High Grade Serous Ovarian Cancer (HGSOC) is a histopathological diagnosis and may represent multiple diseases at a molecular level. We investigated whether distinct molecular subgroups may influence treatment choice. The accompanying training set of data has also been deposited in ArrayExpress under...
ORGANISM(S): Homo sapiens 
2021-12-21 | E-MTAB-2570 | biostudies-arrayexpress
ProteomicsA type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS
Acute respiratory distress syndrome (ARDS) is a severe critical condition with a high mortality that is currently in focus given that it is associated with mortality caused by coronavirus induced disease 2019 (COVID-19). Neutrophils play a key role in the lung injury characteristic of non-COVID-19 A...
ORGANISM(S): Homo sapiens (Human) 
2021-02-03 | PXD023834 | Pride
Ards Type i ifn Sars-cov-2 Dexamethasone Neutrophil Covid-19 
UnknownN-WASP involvement in dorsal ruffle formation in mouse embryonic fibroblasts.
Not available
S-EPMC1783773 | biostudies-literature
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