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ProteomicsRat muscle proteome with salbutamol
We have performed a study on the effects of salbutamol (an anabolic agent) on the proteome of rat muscle cells. Salbutamol is a type of beta2 adrenergic agonist, which is known to cause hypertrophy in muscle. This is the 24h post treatment timepoint.
ORGANISM(S): Rattus norvegicus (Rat) 
2011-03-18 | PRD000360 | Pride
ProteomicsA genetically-encoded crosslinker screen identifies SERBP1 as a PKC substrate influencing translation and cell division
The PKC-regulated genome protective pathway provides transformed cells a failsafe to successfully complete mitosis. Despite the necessary role for Aurora B in this programme, it is unclear whether its requirement is sufficient or if other PKC cell cycle targets are involved. To address this, we deve...
ORGANISM(S): Homo sapiens (Human) 
2021-12-09 | PXD029091 | Pride
Human 
ProteomicsStructure of the Cohesin Loader Scc2-Scc4 and its Binding to a Folded Cohesin
The functions of cohesin are central to genome integrity, chromosome organization, and transcription regulation through its prevention of premature sister-chromatid separation and the formation of DNA loops. The loading of cohesin onto chromatin depends on the Scc2-Scc4 complex, however, little is k...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-01-11 | PXD004692 | Pride
Cohesin Cross-linking Cx-ms 
MetabolomicsExperimental and computational approaches for deep metabolome annotation with application to the ecotoxicological model organism Daphnia magna

Identifying metabolomes with greater coverage and confidence is a critical step towards interpreting the metabolic basis of human and environmental health. Yet for over two decades the field of metabolomics has been inhibited by limited metabolite identification. To address this, we developed the...

MTBLS2273 | MetaboLights
ProteomicsA method for independent estimation of false localisation rate for phosphoproteomics
Phosphoproteomics methods are commonly employed in labs to identify and quantify the sites of phosphorylation on proteins. In recent years, various software tools have been developed, incorporating scores or statistics related to whether a given phosphosite has been correctly identified, or to estim...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Homo sapiens (Human) 
2022-06-09 | PXD028840 | Pride
False localisation Phosphorylation 
ProteomicsPhosphodiesterase beta controls cAMP signalling during malaria parasite erythrocyte invasion
Cyclic nucleotide signalling is a major regulator of malaria parasite differentiation. Specific phosphodiesterase (PDE) enzymes are known to control cGMP levels in the parasite, but the mechanisms by with cAMP is regulated remain enigmatic. Here we show that P. falciparum PDEbeta translocates via th...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum Mad71/Papua New Guinea 
2019-02-27 | PXD009157 | Pride
Phosphoproteomics Camp Malaria Tmt Pka Orbitrap 
TranscriptomicsRNA-sequencing of transgenic Arabidopsis seedlings constitutively expressing a Colletotrichum higginsianum effector
The fungal pathogen Colletotrichum higginsianum secretes effector proteins during infection of Arabidopsis. To explore the host processes perturbed by the effector candidate ChEC108 in host plants, transgenic Arabidopsis lines were generated to express AtUBQ10pro:ChEC108-eGFP or AtUBQ10pro:ChEC108^D...
ORGANISM(S): Arabidopsis thaliana 
2026-05-21 | E-MTAB-16996 | biostudies-arrayexpress
ProteomicsToxoplsama Gondii whole proteome study
MS/MS dataset for proteogenomics study of Toxoplasma gondii. The dataset was searched against the official v9 gene model from ToxoDB, and the alternate panels of proteins predicted from RNA-SEQ evidences.
ORGANISM(S): Toxoplasma gondii RH 
2015-02-09 | PXD000297 | Pride
Toxoplasma Proteogenomics 
TranscriptomicsModulation of murine bone marrow derived dendritic cells by IL-4
The archetypal Th2 cytokine interleukin 4 (IL-4) has previously been shown to alternatively activate dendritic cells (DCs) both in vitro and in vivo.To more fully understand the impact of IL-4 dependent alternative activation of DCs, we used mRNA microarrays to define their transcriptional profile. ...
ORGANISM(S): Mus musculus 
2015-04-28 | E-GEOD-59868 | biostudies-arrayexpress
UnknownBlack people in Ukraine: A content analysis of TikTok videos documenting discrimination against Black people attempting to flee at the onset of the 2022 Russo-Ukrainian war.
Not available
S-EPMC10953848 | biostudies-literature
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