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ProteomicssAPP a neuroprotective protein in the brain has widespread effects on the proteome of human cortical neurons related to memory mechanisms.
Human glutamatergic neurons in culture were exposed to 1 nM secreted amyloid precursor protein alpha over a time course (0, 2, 6 and 24 h) and changes in the proteome were identified with SWATH-MS.
ORGANISM(S): Homo sapiens (Human) 
2022-04-03 | PXD031704 | Pride
App Alzheimer’s disease Proteome. Sappa Human neuron 
UnknownEthnicity and outcome of young breast cancer patients in the United Kingdom: the POSH study.
Not available
S-EPMC3887284 | biostudies-literature
GenomicsIdentification and Characterization of Hoxa9 Binding Sites in Hematopoietic Cells
The clustered homeobox proteins play crucial roles in development, hematopoiesis and leukemia yet the targets they regulate and their mechanisms of action are poorly understood. Here, we identified the binding sites for Hoxa9 and the Hox cofactor Meis1 on a genome-wide level and profiled their asso...
ORGANISM(S): Mus musculus 
2011-12-04 | E-GEOD-33509 | biostudies-arrayexpress
UnknownBetter Assessment of Illness Study (BASIL) II for Delirium Severity: Study Design, Variables, and Methods.
Not available
S-EPMC12377491 | biostudies-literature
TranscriptomicsThe genome of the zebra finch, a songbird
This study was part of a larger study on the zebra finch genome (Warren et al 2010. Nature). Here we present a summary of the specific experiment on singing-regulated gene expression. To evaluate the genomic landscape of learned vocal communication, we profiled gene expression in the zebra finch son...
ORGANISM(S): Taeniopygia guttata 
2010-05-15 | E-GEOD-19900 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of post-mortem human brain to investigate gender specific gene expression
Gender differences in brain development and in the prevalence of neuropsychiatric disorders such as depression have been reported. Gender differences in human brain might be related to patterns of gene expression. Microarray technology is one useful method for investigation of gene expression in bra...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2164 | biostudies-arrayexpress
UnknownDiscovery of 4-(5-Membered)Heteroarylether-6-methylpicolinamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5.
Not available
S-EPMC11647725 | biostudies-literature
UnknownDiscovery of VU0467319: an M<sub>1</sub> Positive Allosteric Modulator Candidate That Advanced into Clinical Trials.
Not available
S-EPMC11697341 | biostudies-literature
UnknownPredicting seizure recurrence after an initial seizure-like episode from routine clinical notes using large language models: a retrospective cohort study.
Not available
S-EPMC10695164 | biostudies-literature
UnknownIbrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: an open-label, multicentre, phase 1b/2 trial.
Not available
S-EPMC4134524 | biostudies-literature
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