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TranscriptomicsTranscription profiling of mouse nmyc misexpression in lung (gain of function)
Understanding how lung progenitor cells balance; proliferation against differentiation is relevant to clinical; disorders such as bronchopulmonary dysplasia of; premature babies and lung cancer. Previous studies have; established that lung development is severely disrupted in; mouse mutants with red...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6077 | biostudies-arrayexpress
ProteomicsProteome of lysate granules using G3BP and ASPL, and changes in the G3BP interactome caused by ASPL depletion
Proteome of lysate granules using G3BP and ASPL, and changes in the G3BP interactome caused by ASPL depletion
ORGANISM(S): Homo sapiens (Human) 
2025-08-16 | PXD059889 | Pride
Ribonucleoprotein granule Aspscr1 Ubxd9 Tug Protein homeostasis Viscoelasticity Aspl Stress granule Rheology Vcp/p97 G3bp Ulk Multisystem proteinopathy 
TranscriptomicsTranscription profiling of mouse wildtype lungs vs. lung hypomorphic for nmyc
comparison of expression of wildtype lungs and lungs with hypomorphic expression of nmyc. the lungs were pooled from several biological samples. The hypomorphoic mutant was orignally published in Moens CB et al [PMID: 1577267]. this is part of a larger collection of data comparing nmyc misexpression...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6079 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse kideney FROM beta catenin deficient animals vs controls AT E12.5
We generated a murine genetic model of beta-catenin deficiency targeted to the ureteric bud cell lineage to study the role of beta-catenin mediated Wnt signaling during ureteric morphogenesis. Experiment Overall Design: A comparison was made between triplicate samples of E12.5 kidneys from either no...
ORGANISM(S): Mus musculus 
2008-04-04 | E-GEOD-9629 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis Col-0, ein2-5 and ein5-1 ETHYLENE-INSENSITIVE5 encodes a 5 to 3 exoribonuclease required for posttranscriptional regulation
Ethylene is a gaseous plant growth regulator that controls a multitude of developmental and stress responses. Recently, the levels of Arabidopsis EIN3 protein, a key transcription factor mediating ethylene-regulated gene expression, have been demonstrated to increase in response to the presence of e...
ORGANISM(S): Arabidopsis thaliana 
2008-06-13 | E-GEOD-5174 | biostudies-arrayexpress
TranscriptomicsGenetic homogeneity among strains of Clostridium botulinum type A1 with a unique toxin gene cluster organization
Comparative genomic hybridizations were performed to compare bont/A1 strains with an A2-like toxin gene cluster organization to the genome sequenced strain, C. botulinum ATCC 3502. Keywords: comparative genomic hybridization For each hybridization, the reference strain (C. botulinum ATCC 3502) was...
ORGANISM(S): Clostridium botulinum 
2010-05-26 | E-GEOD-10223 | biostudies-arrayexpress
UnknownAKT Inhibition in Solid Tumors With AKT1 Mutations.
Not available
S-EPMC5501365 | biostudies-literature
TranscriptomicsEarly mouse embryo development
Expression profiling of mouse embryos at E2.5, E3.5, E4.25, E4.5, E5.5 E6.0 to identify genes regulated during development of the ICM (inner cell mass), TE (Trophectoderm) and PrE (Primative endoderm) Keywords: development dupicate analysis of time points
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-8339 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human A549 lung cancer cells treated with actinomycin D and sapphyrin PCI-2050 a new class of tumor-selective inhibitors of gene expression.
The goal of this project was to characterize changes in gene expression in response to the anti-cancer agent sapphyrin PCI-2050. Cultured A549 human lung cancer cells were treated with sapphyrin PCI-2050 or actinomycin D.
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-6400 | biostudies-arrayexpress
UnknownRandomized Open-Label Phase II Trial of Apitolisib (GDC-0980), a Novel Inhibitor of the PI3K/Mammalian Target of Rapamycin Pathway, Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma.
Not available
S-EPMC5569691 | biostudies-literature
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