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GenomicsNCI-H1688 cells treated with natural compounds(sanguinarine chloride, cepharanthine and evodiamine), or (+)-JQ-1, or panobinostat, or sanguinarine chloride in combination with panobinostat or (+)-JQ-1.
NCI-H1688 cells treated with natural compounds(sanguinarine chloride, cepharanthine and evodiamine), or (+)-JQ-1, or panobinostat, or sanguinarine chloride in combination with panobinostat or (+)-JQ-1.
PRJNA757981 | ENA
GenomicsComprehensive transcriptome analysis of human myofibroblasts with/without the JQ-1 treatment [mRNA]
Comprehensive transcriptome analysis of human myofibroblasts with/without the JQ-1 treatment [mRNA]
PRJNA589871 | ENA
GenomicsIdentification of microRNA expression patterns in human myofibroblasts with/without the JQ-1 treatment and/or TGF-b
Identification of microRNA expression patterns in human myofibroblasts with/without the JQ-1 treatment and/or TGF-b
PRJNA589870 | ENA
UnknownTargeting SIRT1 synergistically improves the antitumor effect of JQ-1 in hepatocellular carcinoma.
Not available
S-EPMC10692793 | biostudies-literature
GenomicsIdentification of microRNA expression patterns in human myofibroblasts with/without the JQ-1 treatment and/or TGF-b
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that normal parenchyma is progressively replaced by fibrotic foci comprised of myofibroblasts, active differentiated fibroblasts. IPF has an overall poor prognosis with median survival ranging from 2.5 to 3.5 years. The underlying disease...
ORGANISM(S): synthetic construct Homo sapiens 
2020-07-11 | GSE140475 | GEO
TranscriptomicsComprehensive transcriptome analysis of human myofibroblasts with/without the JQ-1 treatment [mRNA]
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that normal parenchyma is progressively replaced by fibrotic foci comprised of myofibroblasts, active differentiated fibroblasts. IPF has an overall poor prognosis with median survival ranging from 2.5 to 3.5 years. The underlying disease...
ORGANISM(S): Homo sapiens 
2020-07-11 | GSE140476 | GEO
UnknownJQ-1 ameliorates schistosomiasis liver granuloma in mice by suppressing male and female reproductive systems and egg development of Schistosoma japonicum.
Not available
S-EPMC9362908 | biostudies-literature
TranscriptomicsNCI-H1688 cells treated with natural compounds(sanguinarine chloride, cepharanthine and evodiamine), or (+)-JQ-1, or panobinostat, or sanguinarine chloride in combination with panobinostat or (+)-JQ-1.
Purpose: we used next generation sequencing to analyze gene expression profiles of NCI-H1688 treated with different drugs and elaborated the combinatorial effect of sanguinarine chloride and panobinostat or (+)-JQ-1.The goals of this study are to compare the drug effect and find out the resonally sy...
ORGANISM(S): Homo sapiens 
2021-08-31 | GSE182821 | GEO
GenomicsBET inhibitor JQ-1 combined with cardamonin can inhibit the invasion and metastasis of triple-negative breast cancer cells
BET inhibitor JQ-1 combined with cardamonin can inhibit the invasion and metastasis of triple-negative breast cancer cells
PRJNA989573 | ENA
ProteomicsHuman proteomics analysis of BRD4 targeted small-molecules in KSHV+ cells by Orbitrap Eclipse and MaxQuant
In this project, we used proteomics to identify and compare protein profile changed in SIM-1, MZ-1, or JQ-1 treated TIVE-LTC, a KSHV long-term infected immortalized endothelial cell line.
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD075129 | Pride
Brd4 Sim-1 Kshv Mz-1 Jq-1 
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