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MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
UnknownClinical Significance of Programmed Death Ligand‑1 and Intra-Tumoral CD8+ T Lymphocytes in Ovarian Carcinosarcoma.
Not available
S-EPMC5268655 | biostudies-literature
ProteomicsSite mapping of PGK1 O-GlcNAcylation
To identify the site(s) of O-GlcNAcylation on PGK1, we transiently co-expressed Flag-tagged PGK1 and OGT in HEK293T cells. After immunoprecipitation using anti-Flag M2 beads and in-gel trypsin digestion, resulted peptides were subjected to mass spectrometry analysis
ORGANISM(S): Homo sapiens (Human) 
2019-11-06 | PXD015659 | Pride
Pgk1 
UnknownA clinically applicable molecular classification for high-grade serous ovarian cancer based on hormone receptor expression.
Not available
S-EPMC4853732 | biostudies-literature
UnknownHomologous recombination repair gene mutations show no survival benefits in Chinese high-grade serous ovarian cancer patients.
Not available
S-EPMC8033363 | biostudies-literature
UnknownHormone receptor expression profiles differ between primary and recurrent high-grade serous ovarian cancers.
Not available
S-EPMC5464832 | biostudies-literature
UnknownTreatment for clear cell carcinoma of the abdominal wall at a tertiary cancer center.
Not available
S-EPMC9233660 | biostudies-literature
UnknownGray-matter structure in long-term abstinent methamphetamine users.
Not available
S-EPMC7146984 | biostudies-literature
UnknownExploring Contraindicated Medications and Corresponding Targeted Genes for Migraine Through Integrated Genetic Approaches.
Not available
S-EPMC12631026 | biostudies-literature
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