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TranscriptomicsRNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis Aging is a multifactorial process where the impact of singular components still remains unclear. Furthermore, previous studies were focused on measuring specific ...
ORGANISM(S): Homo sapiens 
2014-10-23 | E-GEOD-51518 | biostudies-arrayexpress
UnknownCytogenetic prognostication within medulloblastoma subgroups.
Not available
S-EPMC3948094 | biostudies-literature
ProteomicsHistone peptide pull-down H3K4me0-3 +/- H3Q5ser
The interactome to H3 peptides in different H3K4 methylation states and its change upon H3Q5 serotonylation was determined by performing peptide pull-down followed by qMS. Streptaviding beads, saturated with biotinylated H3 peptides in all possible H3K4 methylation states and with presence and absen...
ORGANISM(S): Homo sapiens (Human) 
2025-06-10 | PXD062109 | Pride
Hela H3 H3q5 
TranscriptomicsRNA-seq of Mycobacterium tuberculosis H37Rv treated with alpibectir or a combination of alpibectir and ethionamide against untreated controls
Alpibectir potentiates the activity of ethionamide and prothionamide, which are second-line antibiotics used for tuberculosis treatment. Both are prodrugs whose antibacterial activity depends on bioactivation by oxidases, including the Baeyer-Villiger monooxygenase MymA. Alpibectir binds the transcr...
ORGANISM(S): Mycobacterium tuberculosis 
2025-12-10 | E-MTAB-16253 | biostudies-arrayexpress
TranscriptomicsChip-chip and MIRA-chip from primary skin fibroblasts, derived of matched pairs of early and late donor age
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. Aging is a multifactorial process where the impact of singular components still remains unclear. Furthermore, previous studies were focused on measuring specific...
ORGANISM(S): Homo sapiens 
2014-10-23 | E-GEOD-51517 | biostudies-arrayexpress
TranscriptomicsLNCaP prostate cancer cell lines overexpressing wild-type or GARRPR-mutant Bag-1L
The BF-3 pocket of the androgen receptor (AR) has been identified as an allosteric modulator of the transactivation function of the AR. We now demonstrate that a duplicated GARRPR motif at the N-terminus of the cochaperone Bag-1L functions through this BF-3 domain. Amino acid exchanges in these two ...
ORGANISM(S): Homo sapiens 
2014-02-18 | E-GEOD-51524 | biostudies-arrayexpress
UnknownTherapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
Not available
S-EPMC4962737 | biostudies-literature
ProteomicsnextPP for chromosome-based proteomic research using neXtProt and GENCODE databases
In this study, we introduce a streamlined pipeline using customized and concatenated GENCODE and neXtProt databases with controlled false discovery rate (FDR) for finding GENCODE ASVs and missing proteins while mapping onto single amino acid variants (SAAVs) from Hippocampal dataset.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-07-25 | MSV000081385 | MassIVE
ProteomicsYoun_et_al_RNAbodies_SAINT3112_MSPLIT_DDA (PAIRED with MSV000081426)
This set of submissions contains the mass spectrometry files acquired using Data-Dependent Acquisition mode (DDA), which were paired with Data-Independent Acquisition mode (DIA) files (MSV000081426) for the manuscript by Ji-Young Youn et al. that describes the high-density proximity mapping of RNA b...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-17 | MSV000081945 | MassIVE
ProteomicsYoun_et_al_RNAbodies_SAINT3105_Set3
This set of submissions contains the mass spectrometry files for the manuscript by Ji-Young Youn et al. that describes the high-density proximity mapping of RNA bodies. BioID experiments were performed from Flp-In T-REx HEK293 cells and MS files were acquired on Orbitrap Elite and Orbitrap Velos. D...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-08-04 | MSV000081413 | MassIVE
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