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ProteomicsImmunopeptidomics DIA and DDA Dynamic Range Experiment
The peptide identification sensitivity of the affinity purified immunopeptidome of a JY cell line (Epstein–Barr virus-immortalized B cell lymphoblastoid line, ECACC 94022533, IHW9287) for DDA and DIA experiments was assessed by a linear concentration series. JY cells are homozygous for all HLA-I loc...
ORGANISM(S): Homo sapiens (Human) 
2025-09-04 | PXD024809 | Pride
Dynamic range Dia Immunopeptidomics Hla 
UnknownHLA Class II Presentation Is Specifically Altered at Elevated Temperatures in the B-Lymphoblastic Cell Line JY.
Not available
S-EPMC8724904 | biostudies-literature
UnknownDetection of murine leukemia virus in the Epstein-Barr virus-positive human B-cell line JY, using a computational RNA-Seq-based exogenous agent detection pipeline, PARSES.
Not available
S-EPMC3302299 | biostudies-literature
ProteomicsHuman HLA-DP RSV viral infection JY cell line mass spectrometry raws
49638 JY non-infected cells HLA-DP 49639 JY infected cells HLA-DP
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-18 | MSV000083591 | MassIVE
UnknownEstablishment and Characterization of 10 Human Pancreatic Cancer Cell Lines Including a HER2 Overexpressed Cell Line.
Not available
S-EPMC6867661 | biostudies-literature
TranscriptomicsAnalysis of the enzymes involved in PEN5 carbohydrate metabolism
Dr. Eric Vivier's lab would like to tackle the enzymes involved in PEN5 carbohydrate metabolism. We have generated these cell lines by repeated cell sorting and cell cloning of the parental HSB-2 T cell line and the parental JY B cell line. H+ are PEN5+ HSB-2 cells, H- are PEN5- HSB-2 cells; JY+ are...
ORGANISM(S): Homo sapiens 
2011-06-14 | GSE29931 | GEO
TranscriptomicsAnalysis of the enzymes involved in PEN5 carbohydrate metabolism
Dr. Eric Vivier's lab would like to tackle the enzymes involved in PEN5 carbohydrate metabolism. We have generated these cell lines by repeated cell sorting and cell cloning of the parental HSB-2 T cell line and the parental JY B cell line. H+ are PEN5+ HSB-2 cells, H- are PEN5- HSB-2 cells; JY+ are...
ORGANISM(S): Homo sapiens 
2011-06-14 | E-GEOD-29931 | biostudies-arrayexpress
ProteomicsThe HLA ligandome comprises a limited repertoire of O-GlcNAcylated antigens preferentially associated with HLA-B07:02
Mass-spectrometry based immunopeptidomics has provided unprecedented insights into antigen presentation, not only charting an enormous ligandome of self-antigens, but also cancer neo-antigens and peptide antigens harbouring post-translational modifications. Here we concentrate on the latter, focusin...
ORGANISM(S): Homo sapiens (Human) 
2021-12-03 | PXD028874 | Pride
O-glcnacylation Hla-b07 Mhc Hla class i Immunopeptidomics 
ProteomicsValidation of a high-performance liquid chromatography-tandem mass spectrometry immunopeptidomics assay for the identification of HLA ligands suitable for pharmaceutical therapies
For more than two decades naturally presented, human leukocyte antigen (HLA)-restricted peptides (immunopeptidome) have been eluted and sequenced using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Since, identified disease-associated HLA ligands have been characterized and evaluated as...
ORGANISM(S): Homo sapiens (Human) 
2020-01-15 | PXD012797 | Pride
Validation Mass spectrometry Gmp Cancer immunotherapy Immunopeptidome Lc–ms/ms 
TranscriptomicsThe PARN deadenylase targets a discrete set of mRNAs for decay and regulates cell motility in mouse myoblasts
Almost all cellular mRNAs terminate in a 3M-bM-^@M-^Y poly(A) tail, the removal of which can induce both translational silencing and mRNA decay. Mammalian cells encode many poly(A)-specific exoribonucleases but their individual roles are poorly understood. Here, we undertook an analysis of the rol...
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-35944 | biostudies-arrayexpress
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