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ProteomicsLichtenberg figures in high voltage electrical injury
Lichtenberg figures (LF), also known as a ferning pattern or keraunographic marking, is a pathognomonic skin sign for a lightning strike injury. The true pathophysiology of LF remains unknown. This dataset describes a case of LF following a high voltage electrical injury in which a skin biopsy was t...
ORGANISM(S): Homo sapiens (Human) 
2021-05-28 | PXD011532 | Pride
Tissue response Lactoferrin Lichtenberg figures Electric injury 
ProteomicsConnective tissue regeneration dynamics persistently alter epithelial dynein DNAH10 expression - DNAH10 overexpression in psoriatic lesional epidermis
The objective of this study was to investigate how active dermal connective tissue composition dynamics affect long term protein expression in the epidermis. After surgically removing damaged skin to its full thickness at the site of a deep burn in ten patients, we randomized three adjacent test are...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD010852 | Pride
Human Skin Dermis Burn injury Label-free quantification Epidermis 
ProteomicsAccumulation of acylcarnitines and mitochondrial dysfunction characterize the loss of neonatal myocardial regeneration capacity
Myocardial regeneration capacity declines during the first week after birth and is linked to the adaptation to oxidative metabolism. Utilizing this regenerative window, we characterized the metabolic changes in myocardial injury in 1-day-old regeneration-competent and 7-day-old regeneration-compromi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-04 | MSV000088783 | MassIVE
MetabolomicsGNPS - Accumulation of acylcarnitines and mitochondrial dysfunction characterize the loss of neonatal myocardial regeneration capacity
Myocardial regeneration capacity declines during the first week after birth and is linked to the adaptation to oxidative metabolism. Utilizing this regenerative window, we characterized the metabolic changes in myocardial injury in 1-day-old regeneration-competent and 7-day-old regeneration-compromi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-04 | MSV000088783 | GNPS
TranscriptomicsGene expression profiling of negative-pressure-treated split-thickness skin graft donor site wounds reveals novel effects on epithelialization
Negative-pressure wound therapy (NPWT) is widely used to improve skin wound healing and to accelerate wound bed preparation. Although NPWT has been extensively studied as a treatment for deep wounds, its effect on epithelialization of superficial dermal wounds remains unclear. To clarify the effect ...
ORGANISM(S): Homo sapiens 
2011-10-24 | E-GEOD-33169 | biostudies-arrayexpress
TranscriptomicsBone marrow-derived stromal cells from double transgenic rats (of Sprague-Dawley origin) harboring the human angiotensinogen and human renin genes, and control rats
Hypertension and persistent activation of the renin-angiotensin system (RAS) are predisposing factors for development of acute kidney injury (AKI). Although bone marrow-derived stromal cells (BMSCs) have shown therapeutic promise in treatment of AKI, the impact of pathological RAS on BMSC functional...
ORGANISM(S): Rattus norvegicus 
2014-03-31 | E-GEOD-51593 | biostudies-arrayexpress
TranscriptomicsHuman Skin Transcriptome during Epidermal Wound Healing
In order to clarify the human response of re-epithelialization, we biopsied split-thickness skin graft donor site wounds immediately before and after harvesting, as well as during the healing process 3 and 7 days thereafter. Altogether 25 biopsies from 8 patients qualified for the study. All samples...
ORGANISM(S): Homo sapiens 
2011-04-29 | E-GEOD-28914 | biostudies-arrayexpress
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