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This a model from the article: An integrated model for glucose and insulin regulation in healthy volunteers and type 2 diabetic patients following intravenous glucose provocations. Silber HE, Jauslin PM, Frey N, Gieschke R, Simonsson US, Karlsson MO. J Clin Phar...
2005-01-01 | MODEL1112110004 | BioModels
Lung cancer is the worldwide leading cause of death from cancer. This GEO series correspond to one of the BAC aCGH data sets used as validation cohort for the study: Landscape of somatic allelic imbalances and copy number alterations in human lung cancer, Int J Cancer 2012. Genomic profiling of 78 l...
ORGANISM(S): Homo sapiens 
Lung cancer is the worldwide leading cause of death from cancer. DNA methylation in gene promoter regions is a major mechanism of gene expression regulation that may promote tumorigenesis. However, whether clinically relevant subgroups based on DNA methylation patterns exist in lung cancer is not we...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE29016: Relation between smoking history and gene expression profiles in lung adenocarcinomas GSE29065: Landscape of somatic allelic imbalances and copy number alterations in human lung carcinoma Refer to individual Series
ORGANISM(S): Homo sapiens 
The AllPrep DNA/RNA mini kit (Qiagen) was used for RNA extraction following manufacturer’s instructions. Libraries were prepared using the Illumina TruSeq stranded mRNA protocol and sequenced on the NovaSeq 6000 system at the Center for Translational Genomics (www.ctg.lu.se) in Lund, Sweden. Demulti...
ORGANISM(S): Homo sapiens 
Lung cancer is the worldwide leading cause of death from cancer. Tobacco usage is the major pathogenic factor, however, not all lung cancers can be attributable to smoking. The genetic aberrations that differ between smokers' and never-smokersM-bM-^@M-^Y lung carcinomas remain to a large extent uncl...
ORGANISM(S): Homo sapiens 
Background: Global gene expression profiling has been widely used in lung cancer research to identify clinically relevant molecular subtypes as well as to predict prognosis and therapy response. So far, the value of these multi-gene signatures in clinical practice is unclear and the biological impor...
ORGANISM(S): Homo sapiens 
Combination of reverse- and chemical genetic screens reveals a network of novel angiogenesis inhibitors and targets Drug target identification and validation are bottlenecks in the drug discovery process. Accordingly there is a need to develop new methods to facilitate the development of much-nee...
ORGANISM(S): Mus musculus 
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