Katayama S S - OmicsDI

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Unknown (996)
Transcriptomics (50)
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Homo sapiens (28)
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cellular organisms (1)
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pride (5)
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CHEBI ID

CHEBI:15891 (3)
CHEBI:15971 (3)
CHEBI:16015 (3)
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CHEBI:16347 (3)
CHEBI:16410 (3)
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CHEBI:17596 (3)
CHEBI:17808 (3)
CHEBI:17895 (3)

Metabolite Name

(+/-)-Mevalonolactone (1)
(R)-MALATE (1)
1,3,8-trihydroxy-4-methyl-2,7-diprenylxanthone (1)
1-METHYLADENOSINE (1)
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12(s)-HETE (1)
15(s)-HETE (1)
17-Hydroxypregnenolone sulfate (1)
2'-DEOXYCYTIDINE 5'-DIPHOSPHATE (1)
2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE (1)
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2-3-Dihydroxyisovalerate (1)
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2-4-Quinolinediol (1)
2-Arachidonylglycerol (1)
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2-Deoxy-D-glucose 6-phosphate (1)
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2-Deoxyadenosine (1)
2-Deoxyadenosine 5-diphosphate (1)
2-Deoxyadenosine 5-monophosphate (1)
2-Deoxycytidine (1)
2-Deoxycytidine 5-diphosphate (1)
2-Deoxycytidine 5-monophosphate (1)
2-Deoxyguanosine (1)
2-Deoxyguanosine 5-diphosphate (1)
2-Deoxyguanosine 5-monophosphate (1)
2-Deoxyinosine (1)
2-Deoxyribose 5-phosphate (1)

Study type

Transcription profiling by array (31)
RNA-seq of coding RNA (9)
Comparative genomic hybridization by array (2)
Other (2)
Methylation profiling by array (2)
Transcription profiling by SAGE (1)
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ChIP-seq (1)

Release Date

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2007 (10)
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2005 (5)
1999 (5)
2006 (4)
2000 (4)
2004 (3)
2002 (3)
1998 (3)
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Lab affiliation

Assistant Professor, Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center (1)
DTU BIOENGINEERING Department of Biotechnology and Biomedicine PCET-Protein Glycoscience and Biotechnology Technical University of Denmark 2800 Kgs. Lyngby (1)
Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. (1)
Dept. Medical Biochemistry and Biophysics, Div. Chemistry I, Karolinska Institutet, Stockholm, Sweden (1)
The University of Texas MD Anderson Cancer Center Director, Red & Charline McCombs Institute for the Early Detection and Treatment of Cancer Co-Director, Center for Global Cancer Early Detection Evelyn & Sol Rubenstein Distinguished Chair for Cancer Prevention Professor, Clinical Cancer Prevention-Research Professor, Translational Molecular Pathology (1)

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Towards an understanding of the mechanism of action of praziquantel

Although praziquantel (PZQ) has been used to treat schistosomiasis for over 20 years its mechanism of action remains unknown. We have developed an assay based on the transcriptional response of S. mansoni PR-1 to heat shock to confirm that while 6 week post infection (p.i.) schistosomes are sensitiv...

ORGANISM(S): Schistosoma mansoni

2008-11-10 | E-GEOD-12850 | biostudies-arrayexpress

Interference of hemozoin formation in Schistosoma mansoni by quinine reduces experimental schistosomiasis

Background: The parasitic trematode Schistosoma mansoni is one of the major causative agents of human schistosomiasis, which afflicts 200 million people worldwide. Praziquantel is still the only drug used for schistosomiasis treatment and reduction in drug efficiency has prompting the search for ne...

ORGANISM(S): Schistosoma mansoni

2010-06-24 | E-GEOD-14751 | biostudies-arrayexpress

Murine Schistosoma-Induced Pulmonary Hypertension: Microarray Data

Rationale: Schistosomiasis is one of the most common causes of pulmonary arterial hypertension worldwide, but the pathogenic mechanism by which the host inflammatory response contributes to vascular remodeling is unknown. We sought to identify signaling pathways that play protective or pathogenic ro...

ORGANISM(S): Mus musculus

2013-07-16 | E-GEOD-48936 | biostudies-arrayexpress

A mutation of RNA polymerase β’ subunit (RpoC) converts heterogeneously vancomycin-intermediate S. aureus (hVISA) into ‘slow-VISA’ (sVISA)

Various mutations in the rpoB gene, which encodes the RNA polymerase beta subunit, are associated with increased vancomycin (VAN) resistance in vancomycin-intermediate S. aureus (VISA) and hetero-VISA (hVISA) strains. We reported that rpoB mutations are also linked to the expression of the recently ...

ORGANISM(S): Staphylococcus aureus

2015-05-08 | E-GEOD-65338 | biostudies-arrayexpress

(R,S)-tetrahydropapaveroline production by stepwise fermentation using engineered Escherichia coli.

Not available

S-EPMC4204043 | biostudies-literature

LC-HRMS Metabolomics for Untargeted Diagnostic Screening in Clinical Laboratories: A Feasibility Study

Today's high-resolution mass spectrometers (HRMS) allow bioanalysts to perform untargeted/global determinations that can reveal unexpected compounds or concentrations in a patient’s sample. This could be performed for preliminary diagnosis attempts when usual diagnostic processes and targeted ...

2019-06-06 | MTBLS476 | MetaboLights

Genetic and molecular basis of drug resistance and species-specific drug action in Schistosome parasites

Oxamniquine resistance evolved in the human blood fluke (Schistosoma mansoni) in Brazil in the 1970s. We crossed parental parasites differing ~500-fold in drug response, determined drug sensitivity and marker segregation in clonally-derived F2s, and identified a single QTL (LOD=31) on chromosome 6. ...

ORGANISM(S): Schistosoma mansoni

2013-12-05 | E-GEOD-51847 | biostudies-arrayexpress

Genome-wide transcriptome analysis revealed extensive alternative RNA splicing in gene expression in the zoonotic parasite Schistosoma japonicum

Background: Schistosoma japonicum is a pathogen of the phylum Platyhelminths that causes zoonotic schistosomiasis endemic in China and Southeast Asian countries. Control of the disease has been hampered by the lack of efficient measures. The development of tools for diagnosis of acute and chronic i...

ORGANISM(S): Schistosoma japonicum

2014-09-02 | E-GEOD-58564 | biostudies-arrayexpress

Contributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer