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TranscriptomicsTranscription profiling by array of human metastatic colorectal tumors and definition of signature relating to response to Folfiri and folfox
Using whole genome tumor gene expression profiling in patients treated for metastatic colorectal cancer, we attempted to define a signature able to discriminate between responders and non-responders to first-line chemotherapy.
ORGANISM(S): Homo sapiens 
2011-12-31 | E-MTAB-333 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human gastro-intestinal stromal tumors to validate prognostic signature
We recently established a 67 genes-expression prognostic signature related to genome complexity in sarcomas. We validated this signature in 60 GISTs, determining patient prognosis.
ORGANISM(S): Homo sapiens 
2011-12-16 | E-MTAB-373 | biostudies-arrayexpress
UnknownarrayQualityMetrics--a bioconductor package for quality assessment of microarray data.
Not available
S-EPMC2639074 | biostudies-literature
UnknownImporting ArrayExpress datasets into R/Bioconductor.
Not available
S-EPMC2723004 | biostudies-literature
TranscriptomicsTranscription profiling of humoral resistance to the CTL after phenotypical and functional study of the resistant clone IGR-HeuR8
From a tumoral line IGR-Heu; resulting from a biopsy of the primitive tumour of a patient reached of a bronchial cancer not with small cells (NSCLC); we established; by successive co-cultures of this line with the autologous CTL (clone T H161); a resistant line to the cytotoxic lysis induced by H16...
ORGANISM(S): Homo sapiens 
2006-01-23 | E-TABM-71 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human TRAIL-resistant metastatic vs primary TRAIL-sensitive melanoma cells
T1 and G1 are the two melanoma cell lines, established from primary tumor (T1) and lymph node metastases (G1) of a 77 years old male patient. While G1 cells were resistant to TRAIL (TNF-related apoptosis-inducing ligand) mediated cell death, T1 cells exhibited a high dose- and time-dependent sensiti...
ORGANISM(S): Homo sapiens 
2006-01-01 | E-MEXP-247 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cell lines treated with cytochalasin D and nocodazole with the aim of characterising tetraploid clones
During the oncogenic process, tetraploidy is a candidate intermediate stage leading from diploidy to aneuploidy. The aim of our experiment was to establish tetraploid clones and to characterize their transcriptome.
ORGANISM(S): Homo sapiens 
2006-03-01 | E-TABM-70 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human tetraploid and polyploid (8N and 16N) megakaryocytes to identify genes which are up and down regulated during megakaryocyte differentiation/polyploidization
The aim of the experiment was to characterize by a pan-genomic approach genes which are continuously up and down regulated during polyploidization during megakaryocyte differentiation.
ORGANISM(S): Homo sapiens 
2007-04-16 | E-TABM-133 | biostudies-arrayexpress
GenomicsPharmacological and genomic profiling identifies NFκB-targeted treatment strategies for mantle cell lymphoma
Mantle cell lymphoma (MCL) is an aggressive malignancy characterized by poor prognosis, underscoring the need for novel therapeutic strategies1. In this study, we employed large-scale pharmacological profiling of 16 pathway inhibitors across more than 100 hematological cell line models to identify n...
EGAS00001000622 | EGA
Genomicsena-DATASET-BCCA-06-12-2013-17:57:13:627-21 - samples
Complete set of bam files associated with study EGAS00001000622
EGAD00001000702 | EGA
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