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TranscriptomicsKCl Stress in Desulfovibrio vulgaris Hildenborough (Series 1)
Increased salinity constitutes an important and frequent fluctuation faced by D. vulgaris in its natural habitat. Using data from microarray experiments, we investigated the effects of excess KCl on D. vulgaris. Keywords: stress response, time course Comparison of cells treated with 250mM KCl to unt...
ORGANISM(S): Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough 
2010-06-11 | E-GEOD-4515 | biostudies-arrayexpress
ProteomicsPhosphoproteome of five-minute KCl-depolarised mouse cultured hippocampal neurons
Cultured hippocampal neurons from mice were treated with high concentration KCl for five minutes to depolarise the plasma membrane and model sustained brain activity. A high KCl condition was compared to low KCl using phosphoproteomics. Phosphopeptides were enriched from trypsin digested bio-replica...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-15 | PXD020232 | Pride
Neurons Depolarisation Phosphoproteome Mouse Hippocampal Tau Kcl Lc-ms/ms 
TranscriptomicsComparison of gene regulation by Gcn5 under KCl stress in S. cerevisiae and S. pombe
This is parallel comparison of gene regulation by Gcn5 in evolutionarily divergent yeasts S. pombe and S. cerevisiae. Our study showed Gcn5 is required for a similar spectrum of stress responses in both organisms, including the response to KCl. This DNA microarray studies is to find conserved or div...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-5218 | biostudies-arrayexpress
TranscriptomicsExpression analysis of big neurospheres generated in vitro
Expression analysis of neurospheres generated in vitro treated by potassium chloride (KCl) and norepinephrine Neurospheres generated in vitro were treated with norepinephrine or potassium chloride. Gene expression analysis was then carried out to identify genes that are up or down regulated due to c...
ORGANISM(S): Mus musculus 
2015-06-12 | E-GEOD-67304 | biostudies-arrayexpress
TranscriptomicsCharaterization of genetic alterations and gene expression signatures found in BCR-ABL inhibitor-resistant KCL-22 subpopulations and single clones
KCL-22 is a chronic myeloid leukemia (CML) cell line derived from a patient in blast crisis phase and harbors the BCR-ABL translocation. The catalytic (ATP-competitive) BCR-ABL inhibitors imatinib and nilotinib have dramatically improved CML patient outcome, but the development of resistance remains...
ORGANISM(S): Homo sapiens 
2014-10-07 | E-GEOD-62121 | biostudies-arrayexpress
TranscriptomicsChronic potassium chloride (KCl) treatment induced gene expression changes in Drosophila head
We have recently developed a Drosophila behavioral- and transcriptomic- based (systems) model of chronic pentylenetetrazole induced locomotor plasticity. Pharmacological validation at behavioral level and at the level of fly head microarray gene expression shows that the model is of potential value ...
ORGANISM(S): Drosophila melanogaster 
2010-05-25 | E-GEOD-10808 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human and mouse stem-cell derived neurons and mouse primary cortical neurons after KCl-induced membrane depolarization against controls.
This experiment comprises RNA-seq data used to study evolutionary differences between humans and mice in neuronal activity-dependent transcriptional responses. Activity-dependent transcriptional responses in developing human stem cell-derived cortical neurons were compared with those induced in deve...
ORGANISM(S): Mus musculus 
2017-02-16 | E-MTAB-5489 | biostudies-arrayexpress
ProteomicsBovine Liver Membrane Preparation
We optimized an SDS depletion protocol involving KCl to precipitate the surfactant from intact proteins in the presence of urea at high pH. Provided is a comparison of 4 samples preciipitated at low pH (8) vs high pH (12), with (8 M) vs without (0 M) urea.
ORGANISM(S): Bos taurus (Bovine) 
2025-08-04 | PXD061512 | Pride
Urea Ph Sds depleted Kcl preciptation 
TranscriptomicsExposure of Salmonella enterica serovar Typhimurium to three humectants used in the food industry: NaCl, KCl and glycerol
Salmonella Typhimurium was exposed to NaCl, KCl and glycerol (equilibrated to the same water activity) for 1, 6 and 24 h after which the expression profiles were examined using microarray. An non-exposed early stationary phase culture grown in LB medium was used as the control. Carried out using 3 b...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2015-06-15 | E-GEOD-69857 | biostudies-arrayexpress
GenomicsTopo1cc siganls are presented at the KCl induced acutely activated enhancers [CUT&RUN]
Topo1cc siganls are presented at the KCl induced acutely activated enhancers [CUT&RUN]
PRJNA770273 | ENA
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