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ProteomicsRegulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα
Progenitor cells at the basal layer of skin epidermis play an essential role in maintaining tissue homeostasis and enhancing wound repair in skin. The proliferation, differentiation, and cell death of epidermal progenitor cells have to be delicately regulated, as deregulation of this process can lea...
ORGANISM(S): Homo sapiens (Human) 
2020-05-13 | PXD015673 | Pride
Deubiquitination Kdf1 Silac Skin Ikkα Epidermal differentiation Qe-ms 
GenomicsKDF1 novel mutation
Detection of the novel c.812A>C (p.Lys271Thr) mutation in KDF1 using whole exome sequencing.
PRJEB85549 | ENA
GenomicsEffect of epithelial depletion of Kdf1 on gene expression alteration during tooth crown development
Effect of epithelial depletion of Kdf1 on gene expression alteration during tooth crown development
PRJNA1117441 | ENA
TranscriptomicsEffect of epithelial depletion of Kdf1 on gene expression alteration during tooth crown development
In our study, we observed that mice lacking epithelial Kdf1 exhibited rounded and blunt molar cusps, accompanied by abnormal folding of dental epithelium, suggesting that epithelial Kdf1 played a regulatory role in molar crown morphogenesis. Nevertheless, the mechanism within dental epithelium regul...
ORGANISM(S): Mus musculus 
2024-06-02 | GSE268481 | GEO
UnknownKDF1, a Novel Tumor Suppressor in Clear Cell Renal Cell Carcinoma.
Not available
S-EPMC8201614 | biostudies-literature
UnknownRegulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
Not available
S-EPMC7202209 | biostudies-literature
UnknownKDF1 promotes ameloblast differentiation by inhibiting the IKK/IκB/NF-κB axis.
Not available
S-EPMC11649965 | biostudies-literature
UnknownKDF1 Novel Variant Causes Unique Dental and Oral Epithelial Defects.
Not available
S-EPMC9604338 | biostudies-literature
UnknownA Novel KDF1 Variant is Associated With Multiple Natal Teeth, Tooth Agenesis, and Root Maldevelopment.
Not available
S-EPMC12240073 | biostudies-literature
UnknownForward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells.
Not available
S-EPMC3841015 | biostudies-literature
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