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MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownAnnual Average Changes in Adult Obesity as a Risk Factor for Papillary Thyroid Cancer: A Large-Scale Case-Control Study.
Not available
S-EPMC4782863 | biostudies-literature
MetabolomicsAcupuncture Synergized With Bortezomib Improves Survival of Multiple Myeloma Mice via Decreasing Metabolic Ornithine
Multiple myeloma (MM) is a hematological malignancy worldwide in urgent need for novel therapeutic strategies. Since Velcade (bortezomib) was approved for the treatment of relapsed/refractory MM in 2003, we have seen considerable improvement in extending MM patient survival. However, most patients a...
2022-02-21 | MTBLS3487 | MetaboLights
UnknownPrognostic Factors Toward Clinically Relevant Radiographic Progression in Patients With Rheumatoid Arthritis in Clinical Practice: A Japanese Multicenter, Prospective Longitudinal Cohort Study for Achieving a Treat-to-Target Strategy.
Not available
S-EPMC4998707 | biostudies-literature
ProteomicsPredictive signatures of 19 antibiotics-induced Escherichia coli proteomes
Identifying the mode of action (MOA) of antibacterial compounds is the fundamental basis for the development of new antibiotics, and the challenge increases with the emerging secondary and indirect effect from antibiotic stress. Although various omics-based system biology approaches of defining anti...
ORGANISM(S): Escherichia coli 
2020-07-23 | PXD016074 | Pride
Quantitative proteomics  label-free  suspension trapping (s-trap)  escherichia coli  antibiotics  mode of action (moa). 
ProteomicsPredictive signatures of 19 antibiotics-induced Escherichia coli proteomes
Identifying the mode of action (MOA) of antibacterial compounds is the fundamental basis for the development of new antibiotics, and the challenge increases with the emerging secondary and indirect effect from antibiotic stress. Although various omics-based system biology approaches of defining anti...
ORGANISM(S): Escherichia coli 
2020-07-23 | PXD016001 | Pride
Quantitative proteomics  label-free  suspension trapping (s-trap)  escherichia coli  antibiotics  mode of action (moa) 
ProteomicsAn ultrafast, reliable and economical approach for quantitative salivary proteomic profiling and oral cancer biomarker discovery
Clinical biomarkers identified by shotgun proteomics require proteins in body fluids or tissues to be enzymatically digested before being separated and sequenced by Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS). How well peptide signals can be resolved and detected is largely dependent o...
ORGANISM(S): Homo sapiens (Human) 
2019-03-12 | PXD012436 | Pride
Strap Saliva Suspension trapping Hela Clinical proteomics Oral squamous cell carcinoma Fasp Biomarker Oscc 
UnknownMolecular signatures and functional analysis of beige adipocytes induced from in vivo intra-abdominal adipocytes.
Not available
S-EPMC6093709 | biostudies-literature
ProteomicsPredictive Signatures of 19 Antibiotic-Induced Escherichia coli Proteomes
Identifying the mode of action (MOA) of antibacterial compounds is the fundamental basis for the development of new antibiotics, and the challenge increases with the emerging secondary and indirect effect from antibiotic stress. Although various omics-based system biology approaches are currently av...
ORGANISM(S): Escherichia Coli K-12 (ncbitaxon:83333) 
2020-10-09 | MSV000086253 | MassIVE
UnknownFunctional Network of the Long Non-coding RNA Growth Arrest-Specific Transcript 5 and Its Interacting Proteins in Senescence.
Not available
S-EPMC7987947 | biostudies-literature
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