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ProteomicsProteomic analysis of integrin-associated adhesion complexes isolated from cells treated with DMSO or FAK inhibitor
Human foreskin fibroblast cells were spread on fibronectin (FN) for 1 h and treated with DMSO or FAK inhibitor (3 uM, AZ13256675 (termed AZ675 for short)) for 1 h. Integrin-associated adhesion complexes isolated from these cells were analysed by mass spectrometry to determine changes in adhesion com...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-08-23 | MSV000080089 | MassIVE
ProteomicsMesenchymal stem cell integrin-associated complexes
The composition and stiffness of the extracellular matrix (ECM) environment that surrounds Multipotent mesenchymal stem cells (MSCs) stem cells dictates transcriptional programming, thereby affecting stem cell lineage decision-making. Cells sense force between themselves and their microenvironment ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079956 | MassIVE
UnknownModerate-to-vigorous physical activity as a mediator between sedentary behavior and cardiometabolic risk in Spanish healthy adults: a mediation analysis.
Not available
S-EPMC4593196 | biostudies-literature
TranscriptomicsComparison of undifferentiated ES cell lines HM1, IMT11, SHBL6.3
3 different ES cell lines were compared in order to determine whether there are significant expression profile differences between ES cell lines, or whether the constraints of maintaining pluripotency in culture force a similar expression profile on cell lines derived from disparate sources. Our res...
ORGANISM(S): Mus musculus 
2007-08-03 | E-GEOD-8625 | biostudies-arrayexpress
TranscriptomicsSuccessful and failed human liver regeneration are characterized by the coordinated expression of distinct microRNAs
The liverM-bM-^@M-^Ys remarkable capacity to regenerate allows it to carry out vital life-supporting functions despite unrelenting pathogen and toxin-induced injury. Unchecked, this capability also leads to cirrhosis, a burgeoning global disease burden. Existing animal models only partially recapitu...
ORGANISM(S): Homo sapiens 
2013-05-06 | E-GEOD-36146 | biostudies-arrayexpress
TranscriptomicsHuman PGC commitment shares key gene dynamics to mouse, but owns a unique PRDM14 expression pattern
The molecular mechanisms of human primordial germ cell (PGC) specification are poorly understood due to the inaccessibility of cell materials and the lack of an alternative in vitro model that enables tracking of the earliest stages of germ cell development. Here, we introduce a defined and efficie...
ORGANISM(S): Homo sapiens 
2015-04-06 | E-GEOD-53498 | biostudies-arrayexpress
TranscriptomicsRNA-Seq based characterization of long non-coding RNA involved in respiratory viruses pathogenesis
We aimed at systematically inferring the regulatory functions of host lncRNAs in response to influenza A virus (IAV) and severe acute respiratory syndrome coronavirus (SARS-CoV) in the mouse model, using a ‘guilt-by-association’ approach which relies on finding which lncRNAs have similar expression ...
ORGANISM(S): Mus musculus 
2014-05-05 | E-GEOD-52405 | biostudies-arrayexpress
UnknownMarkers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling.
Not available
S-EPMC9462470 | biostudies-literature
UnknownThe association of skin intrinsic fluorescence with type 1 diabetes complications in the DCCT/EDIC study.
Not available
S-EPMC3781515 | biostudies-literature
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
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