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UnknownWeekly docetaxel and gemcitabine in previously treated metastatic esophageal squamous cell carcinoma.
Not available
S-EPMC4394089 | biostudies-literature
ProteomicsTissue-specific in vivo mitochondrial matrix proteome profiling in mouse
Targeting proximity labeling enzymes to specific cellular locations is a viable strategy for profiling subcellular proteomes with minimal perturbance to normal physiology. Here, we generate transgenic mice expressing a mitochondrial matrix-targeted ascorbate peroxidase (MTS-APEX2) to enable analysis...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2023-08-31 | PXD026793 | Pride
Coenzyme q Proximity labeling Mitochondrial proteome Apex Rtn4ip1 Nadph Muscle Lc-ms/ms 
ProteomicsDynamic tracking and identification of tissue-specific secretory proteins in the circulation of live mice
Accurate analysis of tissue-specific secretory proteins in blood plasma can provide valuable information regarding therapeutic target development but current approaches are mostly limited to ex vivo proteomic analysis. Here, we developed an in situ secretory protein labeling technology using endopla...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2021-08-06 | PXD025141 | Pride
Proteomics Proximity labeling Turboid 
ProteomicsGmax - Seed, iBAQ (Minetal,jproteomics2017)
abundance based on iBAQ, Interaction consistency score: 9.7, Coverage: 7
ORGANISM(S): 3847 
2017-00-00 | 2413455250 | PAXDB
ProteomicsDesign, Implementation and Multisite Evaluation of a System Suitability Protocol for the Quantitative Assessment of Instrument Performance in Liquid Chromatography-Multiple Reaction Monitoring-MS (LC-MRM-MS)
Multiple reaction monitoring (MRM) mass spectrometry coupled with stable isotope dilution (SID) and liquid chromatography (LC) is increasingly used in biological and clinical studies for precise and reproducible quantification of peptides and proteins in complex sample matrices. Robust LC-SID-MRM-MS...
ORGANISM(S): Bos Taurus 
2018-07-23 | PXD010535 | panorama
ProteomicsAn Anatomically Resolved Comprehensive Mouse Brain Proteome
A mouse brain protein atlas that covers 17 surgically distinctive neuroanatomical regions of the adult mouse brain, each less than 1mm3 in size.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-06-01 | MSV000079789 | MassIVE
ProteomicsParkinson's disease mouse brain proteome profiling
We compared the proteome from a vulnerable region (Substantia nigra pars compacta, SNc) of wild-type and Parkinsonian mice to that of an adjacent, less vulnerable, region (Ventral tegmental area, VTA) and identified several proteins which exhibited both spatiotemporal- and genotype-restricted change...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-12-25 | MSV000080437 | MassIVE
ProteomicsInsights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis
Pulmonary alveolar microlithiasis is an autosomal recessive lung disease caused by a deficiency in the pulmonary epithelial Npt2b sodium-phosphate co-transporter that results in accumulation of phosphate and formation of hydroxyapatite microliths in the alveolar space. The single cell transcriptomic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-02-16 | MSV000091302 | MassIVE
UnknownErtugliflozin and Slope of Chronic eGFR: Prespecified Analyses from the Randomized VERTIS CV Trial.
Not available
S-EPMC8729577 | biostudies-literature
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
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