Sort   by:  
 Page size 
UnknownApplication of human umbilical cord blood-derived mesenchymal stem cells in disease models.
Not available
S-EPMC3097922 | biostudies-literature
ProteomicsChanges in proteome upon mTOR activation
mTOR activation has been known to affect protein synthesis. To identify molecular signatures in transcriptome that could enhance protein synthesis, RNA-seq and quantitative proteomics studies were conducted using WT and TSC1 null MEFs. In this study, we found that the activation of mTOR leads to gen...
ORGANISM(S): Mus musculus (Mouse) 
2015-06-16 | PXD002006 | Pride
3'utr shortening Ubiquitin-mediated proteolysis Alternative polyadenylation Mtor 
TranscriptomicsWhole transcriptome analyses of six thoroughbred horses before and after exercising using RNA-Seq
We sequenced the whole mRNA of six thoroughbred horse (Equus caballus) blood and muscle tissues before and after exercising, generating a total of 1.3 billion short reads with 90-bp pair-end sequences from 24 samples. Comparing with current genome annotation, we identified 32,361 unigene clusters sp...
ORGANISM(S): Equus caballus 
2013-05-01 | E-GEOD-37870 | biostudies-arrayexpress
TranscriptomicsRescue of KRAS suppression in HCT116 colon cancer cell line
Cancer cells that express oncogenic alleles of RAS typically require sustained expression of the mutant allele for survival, but the molecular basis of this oncogene dependency remains incompletely understood. To identify genes that can functionally substitute for oncogenic RAS, we systematically ex...
ORGANISM(S): Homo sapiens 
2014-07-22 | E-GEOD-55942 | biostudies-arrayexpress
UnknownDichotomous intronic polyadenylation profiles reveal multifaceted gene functions in the pan-cancer transcriptome.
Not available
S-EPMC11541570 | biostudies-literature
TranscriptomicsKRAS and YAP1 converge to regulate EMT and tumor survival
Cancer cells that express oncogenic alleles of RAS typically require sustained expression of the mutant allele for survival, but the molecular basis of this oncogene dependency remains incompletely understood. To identify genes that can functionally substitute for oncogenic RAS, we systematically ex...
ORGANISM(S): Mus musculus 
2014-07-27 | E-GEOD-56175 | biostudies-arrayexpress
TranscriptomicsMajor Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands
We examined the major patterns of changes in gene expression in mouse splenic B cells in response to stimulation with 33 single ligands for 0.5, 1, 2, and 4 h. We found that ligands known to directly induce or costimulate proliferation, namely, anti-IgM (anti-Ig), anti-CD40 (CD40L), LPS, and, to a l...
ORGANISM(S): Mus musculus 
2004-12-08 | E-GEOD-2050 | biostudies-arrayexpress
ProteomicsDesign, Implementation and Multisite Evaluation of a System Suitability Protocol for the Quantitative Assessment of Instrument Performance in Liquid Chromatography-Multiple Reaction Monitoring-MS (LC-MRM-MS)
Multiple reaction monitoring (MRM) mass spectrometry coupled with stable isotope dilution (SID) and liquid chromatography (LC) is increasingly used in biological and clinical studies for precise and reproducible quantification of peptides and proteins in complex sample matrices. Robust LC-SID-MRM-MS...
ORGANISM(S): Bos Taurus 
2018-07-23 | PXD010535 | panorama
UnknownGenetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.
Not available
S-EPMC5381275 | biostudies-literature
UnknownAssessment of Discrepancies Between Follow-up Infarct Volume and 90-Day Outcomes Among Patients With Ischemic Stroke Who Received Endovascular Therapy.
Not available
S-EPMC8571657 | biostudies-literature
Sort   by:  
 Page size