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MetabolomicsCeramide Promotes Lytic Reactivation of Epstein-Barr Virus in Gastric Carcinoma
Epstein-Barr virus (EBV) has a lifelong latency period after initial infection. Rarely, however, when the EBV immediate early gene BZLF1 is expressed by a specific stimulus, the virus switches to the lytic cycle to produce progeny viruses. We found that EBV infection reduced levels of various cerami...
2023-12-20 | MTBLS7649 | MetaboLights
MetabolomicsMetabolomic analysis on Microcystis aeruginosa cells under various amino acid supplementation conditions
Threonine, an essential amino acid for translation, exhibits toxicity towards slow-growing cyanobacteria. This prompted us to perform transcriptomic and proteomic analyses using Microcystis aeruginosa cells treated with threonine, revealing a noteworthy upregulation of thrC, annotated as pyridoxal 5...
2025-04-02 | MTBLS11852 | MetaboLights
MetabolomicsThe Green Tea Modulates Large Intestinal Microbiome and Exo/Endogenous Metabolome altered through Chronic UVB-exposure (Endogenous assays)
The attenuating effects of green tea supplements (GTS) against the ultraviolet (UV) radiation induced skin damages are distinguished. However, the concomitant effects of GTS on the large intestinal microbiomes and associated metabolomes are largely unclear. Herein, we performed an integrated microbi...
2018-09-14 | MTBLS527 | MetaboLights
UnknownOptimal extraction conditions and quantification of lignan phytoestrogens in cereal grains using targeted LC-MS/MS.
Not available
S-EPMC11201688 | biostudies-literature
ProteomicsComprehensive proteomics analysis to distinguish follicular adenoma and follicular thyroid carcinoma from indeterminate thyroid nodules.Comprehensive proteomics analysis to distinguish follicular adenoma and follicular thyroid carcinoma from indeterminate thyroid nodules
In this study, a total of 202 formalin fixed paraffin embedded (FFPE) thyroid tissues including 62 of benign nodules, 72 of follicular adenoma, and 68 of follicular thyroid carcinoma were used for the analyses. Here, through global FFPE proteomic analysis, proteins differentially expressed by group ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD043154 | Pride
Human Lc-msms Thyroid tumor Ffpe Follicular adenoma Follicular thyroid carcinoma 
ProteomicsComparative analysis of proteomics between lymphocyte-rich hepatocellular carcinoma and hepatocellular carcinoma formalin fixed and paraffin embedded tissues
In this study, the proteomic tissue proteins were analyzed using LC-MS. Fifteen lymphocyte-rich HCC formalin fixed and paraffin embedded (FFPE) tissues, 15 adjacent normal FFPE tissues, and 15 HCC FFPE tissues were analyzed. More than 4,000 liver tissue proteins have been identified by high-sensitiv...
ORGANISM(S): Homo sapiens (Human) 
2024-02-21 | PXD037022 | Pride
Human Lc-msms Hepatocellular carcinoma Formalin fixed and paraffin embedded tissues Lymphocyte-rich hepatocellular carcinoma 
ProteomicsProteomic analysis of Methylomonas DH-1 AlaRS mutant versus wildtype
The AlaRS mutant of Methylomonas DH-1 showed different lactate tolerance compared to the wild type. Proteomic analysis was conducted to find out what protein changes are related to this reason in the AlaRS mutant strain.
ORGANISM(S): Methylomonas sp. 
2026-02-09 | PXD044904 | Pride
Alars Methylomonas dh-1 
ProteomicsHuh-7 exosomes and HBV
Hepatitis B virus (HBV) infection could cause hepatitis, liver cirrhosis and hepatocellular carcinoma. HBV-mediated pathogenesis is only partially understood, but X protein (HBx) reportedly possesses oncogenic potential. Exosomes are small membrane vesicles with diverse functions released by various...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080794 | MassIVE
ProteomicsUSF2 interacted proteins in HEK293T cells
We found that USF2 is repressor of lysosomal genes. To find the interacting co-repressor complex of USF2, we performed USF2 complex purification and mass spectrography.
ORGANISM(S): Homo sapiens (Human) 
2024-09-11 | PXD050434 | Pride
Gfp-trap Usf2 Lc-ms/ms 
MetabolomicsDeciphering the Anti-Obesity Mechanisms of Pharmabiotic Probiotics through Advanced Multiomics Analysis
Probiotics with 'Pharmabiotic' properties are increasingly recognized as effective tools for combating obesity by altering gut microbiota and reducing body fat. However, the molecular mechanisms underlying their anti-obesity effects remain largely unexplored due to the absence of a universal methodo...
2025-02-20 | MTBLS12185 | MetaboLights
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