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UnknownWeekly docetaxel and gemcitabine in previously treated metastatic esophageal squamous cell carcinoma.
Not available
S-EPMC4394089 | biostudies-literature
MetabolomicsAn Integrated Biochemical, Proteomics, and Metabolomics Approach for Supporting Medicinal Value of Panax ginseng Fruits (GC-MS assay)
Panax ginseng roots are well known for their medicinal properties and have been used in Korean and Chinese traditional medicines for 1000s of years. However, the medicinal value of P. ginseng fruits remain poorly characterized. Using gas chromatography-time of flight mass spectrometry (GC-TOF MS), 6...
2016-11-18 | MTBLS350 | MetaboLights
UnknownIntegrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.
Not available
S-EPMC4062710 | biostudies-literature
Genomicswhole exome sequencing of Korean hepatocellular carcinomas
Data Access Committee EGAC00001000329
EGAC00001000329 | EGA
ProteomicsTailoring Polymer Surface for Long-term Reliable Xenogeneic-free Culture of Intestinal Stem Cells via Regulated Dynamic Migratory Behavior
Regenerative therapy employing intestinal stem cells (ISCs) holds a great promise for reliable epithelial restoration. However, achieving this goal requires scalable and robust, but fully defined culture platforms that eliminate the use of xenogeneic components while preserving stem cell function. M...
ORGANISM(S): Homo sapiens (Human) 
2025-07-07 | PXD064449 | Pride
Biomaterials Intestinal stem cells Plasma-treated polymers Cytoskeletal dynamics Surface engineering Regenerative medicine 
TranscriptomicsmiR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4
we identified novel age-related microRNAs through comparative analysis of miRNA expression profiles in young and old myoblasts using next generation sequencing (NGS) small RNA profiles of young mouse and old mouse were generated by deep sequencing, in each four samples, using Illumina GAIIx
ORGANISM(S): Mus musculus 
2015-09-04 | E-GEOD-66267 | biostudies-arrayexpress
ProteomicsXenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy
Inevitable need for basement membrane extract (BME) with undefined constituents, such as Matrigel, for intestinal stem cell (ISC) culture in traditional system poses a significant barrier that must be overcome for the development of clinical-grade, scalable, ready-to-use ISCs. Here, we propose a fun...
ORGANISM(S): Homo sapiens (Human) 
2024-10-22 | PXD050747 | Pride
Intestinal tissue repair Intestinal stem cell derived from 3d human intestinal organoids (isc3d-hio) Stock banking system Xenogeneic-free culture Functional polymer coating 
ProteomicsGlobal proteomics to study silica nanoparticle-induced cytotoxicity and its mechanisms in HepG2 cells
Silica nanoparticles (SiO2 NPs) are commonly used in medical and pharmaceutical fields. Research into the cytotoxicity and overall proteomic changes occurring during initial exposure to SiO2 NPs is limited. We investigated the mechanism of toxicity in human liver cells according to exposure time [0,...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024206 | Pride
Silica nanoparticles  cytotoxicity  label-free quantification  proteomic analysis  mass spectrometry 
ProteomicsiTRAQ-Based Quantitative Proteomic Comparison of 2D and 3D Adipocyte Cell Models Co-cultured with Macrophages Using Online 2D-nanoLC-ESI-MS/MS
The demand for novel three-dimensional (3D) cell culture models of adipose tissue has been increasing, and proteomic investigations are important for determining the underlying causes of obesity, type II diabetes, and metabolic disorders. In this study, we performed global quantitative proteomic pro...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-26 | PXD014437 | Pride
3d-culture Macrophages Adipocytes Proteomic quantification Itraq 
ProteomicsIntegrated tissue and serum proteomics on magnet-guided photothermal therapy using Au/Fe/Au trilayer nanodiscs
Nanodiscs are emerging as promising nanomaterials for localized therapies as they enable magnetic targeting and near-infrared (NIR) laser–driven photothermal stimulation. In this study, we performed comprehensive proteomic analyses of both tissue and serum from mouse models to elucidate the effects ...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-15 | PXD068909 | Pride
Photothermal therapy Serum Proteomics Tissue Nanodisc 
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