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TranscriptomicsTranscription profiling of orthoptic PC-3/FGF-8b- and PC-3/mock-transfected prostate tumors in nude mice
Our aim was to study the effect of FGF-8 on prostate tumor growth and to identify FGF-8b-associated molecular targets in the orthotopic PC-3 nude mouse model of prostate cancer.
ORGANISM(S): Mus musculus 
2008-03-04 | E-MEXP-1081 | biostudies-arrayexpress
no omics definedTranscription profiling of human PC3 prostate cells transfected with FGF-8b vs control vector
The aim of this study was to identify molecular targets for FGF-8 associated with prostate cancer progression in PC3 prostate cancer cells. PC3 prostate cancer cells were stably transfected with FGF-8b or control vector (mock). Expression of FGF-8 in PC3 cells increased cell growth and MMP-productio...
ORGANISM(S): Homo sapiens 
2009-06-01 | E-MEXP-581 | biostudies-arrayexpress
TranscriptomicsThe Nucleosome Landscape of P. falciparum Reveals Chromatin Architecture and Dynamics of Regulatory Sequences
In eukaryotes, the chromatin architecture has a pivotal role in regulating all DNA-related processes. For P. falciparum, the causative agent of human malaria, the nucleosome landscape of the extremely AT-rich intergenic regulatory regions is largely unexplored. With the aid of a highly controlled MN...
ORGANISM(S): Plasmodium falciparum 
2015-11-25 | E-GEOD-66185 | biostudies-arrayexpress
UnknownMulti-locus identification of Psilocybe cubensis by high-resolution melting (HRM).
Not available
S-EPMC9639532 | biostudies-literature
MetabolomicsImpact of myocardial reperfusion on human plasma lipidome
The primary aim of the study is to investigate the temporal changes in plasma lipidome before and after reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) and their association with myocardial injury. We found that 56% of the identified lipid species were significantly a...
2022-02-07 | MTBLS3839 | MetaboLights
UnknownThe Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.
Not available
S-EPMC6218242 | biostudies-literature
ProteomicsEnhanced hippocampal LTP but typical NMDA receptor and AMPA receptor function in a novel rat model of CDKL5 deficiency disorder
Background: Mutations in the X-linked gene cyclin-dependent kinase-like 5 (CDKL5) cause a severe neurological disorder characterised by early-onset epileptic seizures, autism and intellectual disability (ID). Impaired hippocampal function has been implicated in other models of monogenic forms of aut...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-08-14 | PXD043246 | Pride
Hippocampus Rat Cdk Nmda Brain 
TranscriptomicsPortrait of Transcriptional Expression Profiles Displayed by Different Glioblastoma Cell Lines
Comparison of gene expression profiles displayed by four Glioblastoma cell lines, differing mainly by TP53 mutation, in the absence of any kind of treatment.
ORGANISM(S): Homo sapiens 
2011-12-26 | E-MEXP-3200 | biostudies-arrayexpress
MetabolomicsMetabolic analysis of the response of Pseudomonas putida DOT-T1E strains to toluene using Fourier transform infrared spectroscopy and gas chromatography mass spectrometry
To elucidate any observable metabolic alterations during interactions of several strains of Pseudomonas putida (DOT-T1E, and its mutants DOT-T1E-PS28 and DOT-T1E-18) with the aromatic hydrocarbon toluene, metabolomic approaches were employed. Initially, Fourier-transform infrared (FT-IR) spectroscop...
2016-08-23 | MTBLS319 | MetaboLights
MetabolomicsMetabolomics-Driven Discovery of an Introduced Species and Two Malaysian Piper betle L. Variants
The differences in pungency of 'sirih' imply the probable occurrence of several variants of Piper betle L. in Malaysia. However, the metabolite profiles underlying the pungency of the different variants remain a subject of further research. The differences in metabolite profiles of selected M...
2022-03-21 | MTBLS2585 | MetaboLights
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