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UnknownGenetic interactions between a phospholipase A2 and the Rim101 pathway components in S. cerevisiae reveal a role for this pathway in response to changes in membrane composition and shape.
Not available
S-EPMC2872012 | biostudies-literature
ProteomicsProximity proteomics of the oncoprotein β-catenin
-catenin affects human physiology and pathology through numerous interaction partners, of which many have been discovered by standard affinity purification-based proteomics. However, the interaction landscape of -catenin remains incompletely understood, highlighting a need for new experimental appro...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD067416 | Pride
Β-catenin Proximity proteomics Turboid Bioid 
ProteomicsFOX transcription factors are common regulators of Wnt/β-catenin signaling
The Wnt/β-catenin signaling pathway is a critical regulator of development and stem cell maintenance. Mounting evidence suggests that the context-specific outcome of Wnt signaling is determined by the collaborative action of multiple transcription factors, including members of the highly conserved f...
ORGANISM(S): Homo sapiens (Human) 
2023-04-19 | PXD038811 | Pride
Fox transcription factors Turboid Wnt signaling Lc-ms/ms 
ProteomicsThe oncogenic transcription factor FOXQ1 is a bimodal regulator of Wnt target genes
The forkhead box transcription factor FOXQ1 is aberrantly induced in various cancers, and contributes to tumour growth and metastasis. It has been suggested that the oncogenic potential of FOXQ1 may be explained by its activation of the Wnt/β-catenin signalling pathway. However, the mode of action ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-05 | PXD035624 | Pride
Human Lc ms/ms Hek293t 
ProteomicsThe oncogene FOXQ1 is a selective activator of Wnt/β-catenin signalling
The forkhead box transcription factor FOXQ1 is aberrantly induced in various cancers, and contributes to tumour growth and metastasis. It has been suggested that the oncogenic potential of FOXQ1 may be explained by its activation of the Wnt/β-catenin signalling pathway.However, the mode of action of...
ORGANISM(S): Homo sapiens (Human) 
2022-10-05 | PXD030464 | Pride
Human Lc-msms 
TranscriptomicsMicroRNA miR-223 constrains lethal inflammation during Mycobacterium tuberculosis infection
The molecular mechanisms that control innate cell recruitment during chronic infection and inflammation, such as tuberculosis (TB), are incompletely understood. During TB, myeloid cells infiltrate the lung and sustain local inflammation. We identified microRNA (miR)-223 as one of the most abundant n...
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-39163 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse MH-S cell line with methylglyoxal induces apoptosis and immune response
Mycobacteria-induced apoptosis of macrophages plays an important role in modulation of the host immune response involving TNF-alpha as major cytokine. The underlying mechanisms are still ill-defined. Here, we show for the first time that methylglyoxal (MG) and AGEs levels were elevated during mycoba...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3837 | biostudies-arrayexpress
TranscriptomicsGene expression in M. tuberculosis and M. africanum infected tuberculosis patients prior to and following treatment
Differential gene expression in M. tuberculosis and M. africanum patients under TB treatment Gene expression analysis of whole blood RNA from tuberculosis patients prior to and following treatment
ORGANISM(S): Homo sapiens 
2015-06-05 | E-GEOD-62147 | biostudies-arrayexpress
UnknownCooperation between two periplasmic copper chaperones is required for full activity of the cbb3 -type cytochrome c oxidase and copper homeostasis in Rhodobacter capsulatus.
Not available
S-EPMC4878679 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation of human HepG2 cells SREBP-1 and RNA polII in HepG2 on ENCODE arrays
Chromatin immunoprecipitation of SREBP-1 and RNA polII in HepG2 with detection on ENCODE arrays.
ORGANISM(S): Homo sapiens 
2009-02-16 | E-TABM-530 | biostudies-arrayexpress
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