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ProteomicsThe analysis of PRRSV nucleocapsid interactome
The porcine reproductive and respiratory virus (PRRSV) is a significant swine disease, causing reproductive failure in sows and complex respiratory failure in sows and complex repiratory syndrome in pigs of all ages. PRRSV is an enveloped +ssRNA virus classified within the family Arteriviridae, whic...
ORGANISM(S): Homo sapiens (Human) 
2026-05-01 | PXD044394 | Pride
Prrsv nidovirus arterivirus nucleocapsid interactome 
ProteomicsIntegrated proteomics unveils regulation of cardiac myocytes hypertrophic growth by a nuclear cAMP nanodomain under the control of PDE3A
Signalling by cAMP is organized in multiple distinct subcellular nanodomains regulated by cAMP-hydrolysing phosphodiesterase (PDEs). Cardiac b-adrenergic signalling has served as the prototypical system to elucidate cAMP compartmentalization. Here we employed an integrated interaction and phosphopr...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-03-10 | PXD033773 | Pride
Hypertrophy Sympathetic Phosphodiesterases Adrenegic Camp 
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