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ProteomicsHEK293T MS - Representing dynamic biological networks with multi-scale probabilistic models
As an example of a comprehensive model of signal transduction, we provide a Wnt network that shows remarkable robustness under a range of phenotypical and pathological conditions. Its simulation allows the clarification of controversially discussed molecular mechanisms of Wnt signalling by predictin...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD011835 | Pride
Human Rac1 St-rna knockdown Hek293t Jnk2 Jnk1 
ProteomicsLFQ DIA to analyze the proteome of NPC mutant iNeurons with and without ferric ammonium citrate
Label-free quantification (LFQ) using data-independent acquisition (DIA) on the Orbitrap Astral was performed to analyze the proteome of iNeurons with NPC1 and NPC2 knocked out. The experiment includes the following time points of development: day 0, 4, 8, 16, and 22. All samples were cultured in re...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000095985 | MassIVE
ModelsPredicting Variabilities in Cardiac Gene
Gene interactions in cells can be represented by gene regulatory networks. A Boolean network models gene interactions according to rules where gene expression is represented by binary values (on / off or {1, 0}). In reality, however, the genes state can have multiple values due to biological propert...
4706 | Cell Collective
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