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TranscriptomicsUse of an activated beta-catenin to identify Wnt/beta-catenin pathway target genes in C. elegans, including a subset of collagen genes expressed in late larval development
The Wnt signaling pathway plays a fundamental role during the development of metazoans, where it functions in the regulation of diverse processes including cell fate specification, cell migration, and stem cell renewal. Activation of the beta-catenin dependent or canonical Wnt signaling pathway upr...
ORGANISM(S): Caenorhabditis elegans 
2014-05-13 | E-GEOD-51502 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans embryonic muscle
Background: The force generating mechanism of muscle is evolutionarily ancient; the fundamental structural and functional components of the sarcomere are common to motile animals throughout phylogeny. Recent evidence suggests that the transcription factors that regulate muscle development are also ...
ORGANISM(S): Caenorhabditis elegans 
2008-06-16 | E-GEOD-8462 | biostudies-arrayexpress
UnknownData-directed top-down Fourier-transform mass spectrometry of a large integral membrane protein complex, Photosystem II from Galdieria sulphuraria
Not available
S-EPMC3046778 | biostudies-literature
UnknownCharacterizing Adrenergic Regulation of Glucose Transporter 4-Mediated Glucose Uptake and Metabolism in the Heart.
Not available
S-EPMC10322917 | biostudies-literature
UnknownLate Pleistocene human genome suggests a local origin for the first farmers of central Anatolia.
Not available
S-EPMC6425003 | biostudies-literature
TranscriptomicsDirect genesis of functional rodent and human Schwann cells from skin mesenchymal precursors (human)
Recent reports of directed reprogramming have raised questions about the stability of cell lineages. Here, we have addressed this issue, focusing upon skin-derived precursors (SKPs), a dermally-derived precursor cell. We show by lineage tracing that murine SKPs from dorsal skin originate from mese...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-57518 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans embryonic muscle
Background: ; The force generating mechanism of muscle is evolutionarily ancient; the fundamental structural and functional components of the sarcomere are common to motile animals throughout phylogeny. Recent evidence suggests that the transcription factors that regulate muscle development are also...
ORGANISM(S): Caenorhabditis elegans 
2008-06-16 | E-GEOD-8231 | biostudies-arrayexpress
TranscriptomicsMiz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation
Miz1deltaPOZ mothers feature a lactation defect. In order to identify genes potentially regulated by Miz1 which could explain the observed phenotype and to assess the relative expression of milk protein genes and JAK-STAT pathway components, a genome-wide cDNA microarray was performed using sampl...
ORGANISM(S): Mus musculus 
2014-02-25 | E-MTAB-1718 | biostudies-arrayexpress
UnknownCCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation.
Not available
S-EPMC10416392 | biostudies-literature
GenomicsCharacterization of the Gut-Associated Microbiome in Inflammatory Pouch Complications Following Ileal Pouch-Anal Anastomosis

This study involved evaluation of the tissue associated microbiome of the ileal pouch following surgery for ulcerative colitis (UC) or familial adenomatous polyposis (FAP). Individuals were recruited, with biopsies taken from the ileal pouch and the pre-pouch ileum, microbial DNA was extracted an...

phs000659.v1.p1 | EGA
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